bacteraemia in a patient with Fanconi anaemia after haematopoietic cell transplantation.

Introduction: is an environmental bacterium first detected in 1999. Infections with isolated have been reported in two elderly patients, and were associated with the surgical intervention of artificial objects. We present a case of bacteraemia caused by following haematopoietic cell transplantation (HCT).

Case Presentation: A 10-year-old Japanese boy presented with fever and the swelling of the left cheek 8 days after HCT for the treatment of Fanconi anaemia. Gram-positive, rod-shaped bacteria were isolated from the blood cultures after 5 days incubation. 16S rRNA sequencing, but not mass spectrometry, identified a strain of (1 414 bp, %ID 100 %). The phlegmon did not respond to antimicrobial therapy, but remitted with defervescence after a successful engraftment with teicoplanin and meropenem therapy on day 16 after HCT. The patient experienced recurrence of the bacteraemia, leading to central venous catheter (CVC) line removal. The same strain of was isolated from the cultured tip of the CVC. To our knowledge, this is the first reported case of bacteraemia and was complicated by CVC infection after HCT.

Conclusion: bacteraemia developed in an immunocompromised child. Introduction of artificial objects into the body raises a risk of rare infection with slowly growing environmental bacteria.