Deep eutectic solvents (DES) have garnered significant attention as extraction media owing to their commendable attributes of being environmentally sustainable and the inherent adaptability of DES's versatile physical and chemical characteristics. The present study investigated the effects of deep eutectic solvents on the total contents of anthocyanin, phenolic, and flavonoids, as well as the antioxidant activity of Thai pigmented rice bran extract. The optimal extraction parameters for deep eutectic solvent-based ultrasonic-assisted extraction (DES-UAE) were also determined using the response surface methodology (RSM). The optimal conditions for the extraction of anthocyanins and other antioxidants from pigmented rice bran using a deep eutectic solvent were choline chloride: ethylene glycol (Ch:Eg) at a 1:2 ratio, mixed with 20 % water as a solvent. The ultrasonic-assisted extraction (UAE) at 37 kHz of frequency, 50 °C of temperature, 40 min of extraction time, and a 1:6 g/mL of solid-to-solvent ratio yielded a total anthocyanin content of 4.55 ± 0.09 mg C3G/g DW, a total phenolic content of 26.49 ± 0.62 mg GAE/g DW, a total flavonoid content of 6.57 ± 0.55 mg QE/g DW, and a percent inhibition of DPPH radical of 77.83 ± 1.51. By comparing the antioxidant content that was extracted from three cultivars of pigmented rice, it was found that Leum Pua black rice bran provided significantly higher antioxidant content compared to Hom Nin purple rice bran and Mali Dang red rice bran. This research suggests an achievable, eco-friendly, and effective method for preparing high-quality, consumer-safe Thai rice bran as a raw material for nutraceuticals.
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http://dx.doi.org/10.1016/j.heliyon.2023.e23525 | DOI Listing |
Cureus
January 2025
Electrophysiology, 3Brain AG, Genova, ITA.
The natural product MGN-3 (Biobran) is a defatted, partially hydrolysed rice bran-derived hemicellulose enzymatically modified with an extract of . It has a high proportion of arabinoxylan. It has a protective action against intracerebroventricular streptozotocin-induced murine sporadic Alzheimer's disease and reverses spatial memory deficit in this disease model.
View Article and Find Full Text PDFNat Prod Res
January 2025
Loyola Centre for Research and Development, Xavier Research Foundation, St. Xavier's College Campus, Ahmedabad, Gujarat, India.
Mycophenolic acid (MPA) is an immunosuppressive/antibiotic drug, biologically produced by the fermentation of Penicillium brevicompactum as its secondary metabolite using submerged (SmF) and solid-state (SSF) fermentation processes. In this study, the SSF of (MTCC 1999) was done in optimised conditions to enhance MPA yield. Substrates including basmati and non-basmati rice, barley, oats, cornflakes, rice bran, and wheat bran were 80% moistened and sterilised.
View Article and Find Full Text PDFHeliyon
January 2025
Department of Food Science and Technology, Lahijan Branch, Islamic Azad University, Lahijan, Iran.
This research aimed to produce a multifunctional bread by adding hydrothermally processed rice bran (RB), green tea extract (GTE), and rosemary extract (RE). In the first step, hydrothermal processing was used to reduce the amount of phytic acid in RB, which decreased by 55 %. Based on the acrylamide amount, texture profile analysis, and color parameters, 3 % RB was selected as the optimum concentration in the bread formulation.
View Article and Find Full Text PDFJ Agric Food Chem
January 2025
Department of Agro-Industry, Faculty of Agriculture, Natural Resources and Environment, Naresuan University, 99 Moo 9, Tha Pho, Phitsanulok 65000, Thailand.
This study aimed to evaluate the cholesterol-regulatory effects of lauric-acid-esterified octacosanol (LEO) and oleic-acid-esterified octacosanol (OEO) compared to their unmodified counterparts and to investigate the underlying mechanisms by partially substituting the fat content in obese C57BL/6J mice induced with a high-fat diet (HFD). Rice bran oil and coconut oil were also investigated as they are rich in oleic acid and lauric acid, respectively. The results showed that all supplemented groups significantly inhibited weight gain induced by the HFD, but the groups treated with esterified octacosanol exhibited a more pronounced effect.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
College of Grain Science and Technology, Shenyang Normal University, Shenyang 110034, China. Electronic address:
In this experiment, we investigated the structural properties, digestibility, and variations in antioxidant activity of rice bran-tissue peanut protein (RB-TPP), which was created through high-moisture extrusion between peanut protein powder (PPP) and various additions (0 %, 5 %, 10 %, 15 %, and 20 %) of rice bran (RB). The disulfide bonding and hydrophobic interactions were strengthened, and the hydrogen bonding in the RB-TPP was weakened by adding 5-10 % RB. Additionally, the β-sheet content reached its maximum at RB-10 %, which allowed the hydrophobic groups to be encapsulated ina stable protein network fiber structure, enhancing degree of organization, the thermal stability and digestibility of RB-TPP.
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