Peri-implantitis is one of the most prevalent and impactful complications of dental implant prostheses. This study aimed to identify area focuses and emerging trends in peri-implantitis research. A literature search was conducted in the Web of Science Core Collection (WoSCC), employing a bibliometric approach for data evaluation. VOSviewer and CiteSpace software were used for identifying and analyzing research foci and trends. Between 2001 and 2020, there were 2,346 publications on peri-implantitis. Leaders in number of articles published and collaboration networks were USA and Europe. High-frequency keywords included periodontitis, treatment, prevalence, titanium, follow-up, survival, in vitro, and bone loss. Keyword burst detection analysis revealed epidemiology, outcomes, and impact as emerging research hotspots. The findings suggest a need for more international multicenter clinical studies on peri-implantitis, with future studies likely focusing on prevalence, treatment, and predisposing factors.
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Int Immunopharmacol
January 2025
The Affiliated Stomatological Hospital, Southwest Medical University, Luzhou 646000 Sichuan, China. Electronic address:
Background: Peri-implantitis is an inflammatory bone disease that seriously affects the health of dental implants. Pyroptosis plays an important role in peri-implantitis and inhibition of pyroptosis may point out a new direction for treating the disease. The long non-coding RNA Negative Regulator of Interferon Response (lncRNA NRIR) is closely related to peri-implantitis and may be involved in the process of pyroptosis.
View Article and Find Full Text PDFDent J (Basel)
December 2024
Department of Medicine, Surgery and Dentistry, University of Salerno, Via S. Allende, 84081 Salerno, Italy.
This systematic review evaluated concomitant trends in microbial (total biofilm load and pre-dominant pathogens' counts) and clinical, radiographic, and crevicular variations following (any) peri-implantitis treatment in partially vs. totally edentulous, systemically healthy, non-smoking adults and compared them to peri-implant mucositis treated sites. The study protocol, compliant with the PRISMA statement, was registered on PROSPERO (CRD42024514521).
View Article and Find Full Text PDFDent Med Probl
October 2024
Surgery and Odontostomatology, University of Salamanca, Spain.
Once present, peri-implantitis is difficult to fully eliminate. Surgical interventions show some promising results in fighting the disease, but for the time being, prevention remains the strongest tool.
View Article and Find Full Text PDFBiomedicines
September 2024
Department of Dentistry, SMG SNU Boramae Medical Center, Seoul 07061, Republic of Korea.
In recent years, dental implants have become increasingly popular around the world. However, if the implant is not properly managed, inflammation may occur, and the implant itself may need to be removed. Peri-implantitis is a common inflammation that occurs in dental implants, and various laser treatments have recently been studied to eliminate it.
View Article and Find Full Text PDFHeliyon
August 2024
Stomatological Hospital of Chongqing Medical University, No. 426 Songshi North Road, Chongqing, China.
Background: The application of nanomaterials (NMs) in the treatment of periodontitis and peri-implantitis has shown multifunctional benefits, such as antibacterial properties, immune regulation, and promotion of osteogenesis. However, a comprehensive bibliometric analysis to evaluate global scientific production in this field has not yet been conducted.
Method: We searched for publications related to nanomaterials in periodontitis and peri-implantitis using the WOSCC database.
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