AI Article Synopsis
- A 77-year-old woman diagnosed with wild-type ATTR cardiac amyloidosis presented with symptoms like dyspnea and arrhythmia, along with elevated NT-pro BNP levels.
- Initial imaging using various techniques showed cardiac abnormalities, leading to the initiation of tafamidis treatment.
- After 14 months of treatment, she experienced symptom improvement and reduced NT-pro BNP levels, but imaging results varied, indicating that PiB PET/CT might be more effective than NaF PET/CT in evaluating treatment response.
Article Abstract
We present a 77-year-old woman with wild-type ATTR cardiac amyloidosis (ATTR-CA) who presented with dyspnea, arrhythmia, and elevated NT-pro BNP. Initial imaging including cardiac MRI, PYP scintigraphy, PiB PET/CT and NaF PET/CT revealed cardiac abnormalities. Tafamidis treatment was initiated. After 14 months, symptomatic improvement and reduced NT-pro BNP were observed. Cardiac MRI and PYP scintigraphy showed no significant change and increased NaF accumulation, while PiB PET/CT showed decreased amyloid deposition, suggesting that it may be superior to NaF PET/CT in assessing the therapeutic effect of tafamidis in ATTR-CA.
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| http://dx.doi.org/10.1016/j.nuclcard.2024.101800 | DOI Listing |
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