AI Article Synopsis

  • The study tested the effects of theophylline and steroid-theophylline combination therapy on visual retention and learning in asthmatic children compared to nonasthmatic peers.
  • Children on combination therapy performed worse on cognitive tasks 6-8 hours after steroid treatment, but their performance improved later on.
  • In contrast, children taking only theophylline showed no significant cognitive differences from nonasthmatics, indicating that steroids may impact cognitive performance temporarily.

Article Abstract

Asthmatic children receiving theophylline or steroid-theophylline combination therapy and normal nonasthmatics were given tests of visual retention and paired-associate learning. The performance of children receiving combination therapy was significantly worse than that of the nonasthmatics 6-8 hours after receiving steroid medication, but not 22-24 or 46-48 hours after medication. Children receiving theophylline alone did not differ from nonasthmatics on these tasks. These observations suggest that steroid-inclusive medication regiments can affect cognitive performance.

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http://dx.doi.org/10.3109/02770908609073175DOI Listing

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