Intra-abdominal Venous Thromboses and Their Management.

Acad Radiol

Department of Pediatric Interventional Radiology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Ave, Boston, Massachusetts 02115, USA (M.A.). Electronic address:

Published: August 2024

AI Article Synopsis

  • There is a lack of comprehensive literature on the management of intra-abdominal venous thromboses compared to deep venous thromboses in extremities, with conditions including iliocaval venous obstruction, hepatic venous thrombosis, and others.
  • Doppler ultrasound is the primary imaging tool for diagnosis, while CT and MRI help assess the extent of the thrombus and plan interventions.
  • Treatment typically involves systemic anticoagulation, but catheter-directed thrombolysis, thrombectomy, and TIPS creation show promising results in specific types of intra-abdominal venous thromboses.

Article Abstract

While a plethora of articles discuss management of deep venous thromboses in extremities, there is a relative scarcity of literature comprehensively describing intra-abdominal venous thromboses, and their management. Intra-abdominal venous thromboses include iliocaval venous obstruction (ICVO), hepatic venous thrombosis (HVT), portal venous thrombosis (PVT), renal vein thrombosis (RVT), splenic vein thrombosis (SVT), and gonadal vein thrombosis (GVT); each of which provides unique microenvironmental challenges to management. Doppler ultrasound is the first line imaging modality for diagnosis, and computed tomography and magnetic resonance imaging can help define the extent of thrombus burden and aid with interventional planning. Systemic anticoagulation remains the common medical treatment for intra-abdominal venous thrombosis, however, catheter directed thrombolysis and thrombectomy show positive outcomes in ICVO, HVT, PVT, and RVT, with transjugular intrahepatic portosystemic shunt (TIPS) creation especially beneficial in HVT and PVT. In this review article, we describe pathophysiology, clinical features, imaging findings, and current management options for intra-abdominal venous thromboses.

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Source
http://dx.doi.org/10.1016/j.acra.2023.12.018DOI Listing

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