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Dementia Care Research and Psychosocial Factors.
Alzheimers Dement
December 2024
UK Dementia Research Institute, Care Research and Technology Centre, Imperial College London and the University of Surrey, Guildford, United Kingdom.
Background: Changes in sleep patterns are common in Alzheimer's disease and impact the quality of life of both people living with Alzheimer's (PLWA) and their caregivers. Longitudinal recordings and assessment of night-to-night variations in sleep and physiology can improve our understanding of how sleep influences clinical outcomes and caregiver wellbeing.
Method: We collected sleep diary and contactless sleep technology data (Withings sleep analyser, WSA) in community dwelling PLWA (N = 16, Age = 72.
Individualized temporal patterns drive human sleep spindle timing.
Proc Natl Acad Sci U S A
January 2025
Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA 02115.
Sleep spindles are cortical electrical oscillations considered critical for memory consolidation and sleep stability. The timing and pattern of sleep spindles are likely to be important in driving synaptic plasticity during sleep as well as preventing disruption of sleep by sensory and internal stimuli. However, the relative importance of factors such as sleep depth, cortical up/down-state, and temporal clustering in governing sleep spindle dynamics remains poorly understood.
View Article and Find Full Text PDFGeocultural differences in pre-schooler sleep profiles and family practices: an analysis of pooled data from 37 countries.
Sleep
December 2024
School of Health and Society, University of Wollongong, Australia.
Study Objectives: To examine 1) multidimensional sleep profiles in pre-schoolers (3-6 years) across geocultural regions and 2) differences in sleep characteristics and family practices between Majority World regions (Pacific Islands, Sub-Saharan Africa, Eastern Europe, Northeast Asia, Southeast Asia, South Asia, the Middle East and North Africa, Latin America) and the Minority World (the Western world).
Methods: Participants were 3507 pre-schoolers from 37 countries. Nighttime sleep characteristics and nap duration (accelerometer: n=1950) and family practices (parental questionnaire) were measured.
Night to night variability in obstructive sleep apnea severity, the physiological endotypes and the frequency of flow limitation.
Sleep
December 2024
Monash Lung, Sleep, Allergy and Immunology, Monash Health, Victoria, Australia.
Article Synopsis
- The study investigates night-to-night variability (NtNV) in obstructive sleep apnea (OSA) severity and looks for predictors of this variability.
- 71 OSA patients underwent two sleep studies to analyze their apnea-hypopnea index (AHI), endotypes, and airflow limitations.
- Results revealed significant variability in AHI, but no strong correlations were found between AHI variability and changes in OSA endotypes, suggesting the complexity of predicting OSA severity.
Article Synopsis
- The study aimed to compare manual and automated methods for detecting REM sleep without atonia (RSWA) in patients with REM sleep behavior disorder (RBD) and a control group.
- Researchers evaluated the accuracy of automated RSWA detection through in-laboratory and in-home recordings, finding high agreement with expert scoring and good reliability of results across multiple nights.
- Results showed that automated detection provided a strong ability to differentiate between RBD patients and control subjects, suggesting it could be a useful tool for diagnosing RBD.
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