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Estimating the accumulation and re-accumulation of commercial tobacco, electronic cigarette, and cannabis waste based on a stratified random sample of census blocks.
PLoS One
January 2025
Center for Tobacco and the Environment, San Diego State University, San Diego, California, United States of America.
We investigated the amount and distribution of waste generated by commercial tobacco, electronic cigarette, and cannabis (TEC) use to inform policy options aimed at mitigating the environmental harm caused by these products. Using disproportionate stratified random sampling, we selected 60 census blocks from the eight largest cities in San Diego County, California. We twice surveyed publicly accessible areas in these blocks to quantify TEC waste accumulation and its re-accumulation.
View Article and Find Full Text PDFImpact of Patient Volume on Iodinated Contrast Material Waste with Multidose Contrast Injectors.
Acad Radiol
December 2024
Department of Radiological Sciences, University of California Irvine, Orange, CA 92868. Electronic address:
Background: Multidose iodinated contrast media (ICM) injectors have shown promise in reducing ICM waste. This study aims to evaluate the impact of patient volume on ICM waste reduction in multidose injectors.
Methods: CT studies performed over one-year period with a multidose injector at our emergency CT unit.
Large, protracted, multispecies and multiclonal spread of VIM-type Metallo-ß-Lactamase-Producing Enterobacterales in an Italian Hospital.
J Hosp Infect
December 2024
Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; Clinical Microbiology and Virology Unit, Careggi University Hospital, Florence, Italy. Electronic address:
Background: Carbapenem-resistant Enterobacterales, particularly those producing carbapenemases (CPE), pose a major threat to human health, being listed among critical-priority resistant pathogens by the World Health Organization.
Aim: In this study we report on a large nosocomial spread of CPE of different species producing VIM-type carbapenemases, and on the infection prevention and control measures thata were adopted to contrast the spread.
Methods: Conventional culture and molecular methods were used for detection and identification of VIM-positive CPE (VIM-CPE) causing infections or colonizing patients or present in environmental specimens.
Assessment of potential ecological risk for microplastics in freshwater ecosystems.
Chemosphere
December 2024
Environmental Risk Assessment Center, Gyeongnam Branch Institute, Korea Institute of Toxicology (KIT), Jinju 52834, Republic of Korea. Electronic address:
Microplastics (MPs) are one of the most widespread environmental pollutants, but their risk assessment to freshwater ecosystems has not been clearly investigated. Risk assessment has been constrained by the absence of MP concentration in some environment, the diverse types and shapes of MPs, and limitations of polystyrene (PS)-biased toxicity studies. This study examined exposure to MPs in rivers and lakes worldwide, including China (the Three Gorges Dam & Yangtze River (TGD & YR) and the lakes of Wuhan city (WL)), Vietnam (seven lakes of Da Nang city (7UL)), Europe (the Rhine River (RR)), Finland (Kallavesi Lake (KL)), Argentina (nine lakes in the Patagonia region (9LP)), Brazil (Guaiba Lake (GL)), and South Korea (Nakdong River (NR), Han River (HR), and Anyang Stream (AS)), and assessed the risks to aquatic ecosystems based on the toxicity information and morphology of MPs.
View Article and Find Full Text PDFReduction of postoperative pain and opioid consumption by VVZ-149, first-in-class analgesic molecule: A confirmatory phase 3 trial of laparoscopic colectomy.
J Clin Anesth
December 2024
Department of Anesthesiology and Pain Medicine, Seoul National University, College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea. Electronic address:
Study Objective: VVZ-149 is a small molecule that inhibits the glycine transporter type 2 and the serotonin receptor 5-hydroxytryptamine 2 A. In this Phase 3 study, we investigated the efficacy and safety of VVZ-149 as a single-use injectable analgesic for treating moderate to severe postoperative pain after laparoscopic colectomy.
Design: Randomized, parallel group, double-blind, Phase 3 clinical trial (Trial no.
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