Objectives: To assess foot function in SSc and its association with socio-demographic and clinical factors. To evaluate mobility, foot alterations, foot pain, and foot care in these patients.
Methods: Consecutive SSc patients underwent structured interviews and physical examinations. Disability was assessed using the HAQ disability index (HAQ-DI) and the Scleroderma HAQ (SHAQ). Foot function was measured using the Foot Function Index (FFI), foot pain using a numeric pain scale (NPS), and mobility using the Timed-Up-and-Go test (TUG).
Results: A total of 101 patients were included. Forefoot pain was observed in 50.5%, hindfoot pain in 31.7%, foot ulcers in 6.9%, foot plantar callosities in 38.6%, foot arthritis in 2.97%, hallux valgus in 9.9%, claw toes in 5%, and valgus ankle in 3% of patients. The mean FFI was 3.54 (±2.6), the mean NPS was 6.08 (±3.58), and the mean TUG test result was 10.52 (±6.5) seconds. Higher FFI scores, increased NPS, and prolonged TUG were associated with RP severity, SHAQ and HAQ-DI. Of the 101 patients, 36.6% of patients reported never having had their feet examined, and only 32.7% had had their feet examined within the past year.
Conclusion: Foot dysfunction and pain are common in SSc. Higher FFI scores, increased pain, and prolonged TUG duration were linked to disability (HAQ-DI and SHAQ). These analyses should be considered exploratory and require confirmation in external cohorts. Routine foot examinations were lacking in clinical practice. Improved attention for evaluating and caring for the feet in SSc patients is needed.
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http://dx.doi.org/10.1093/rheumatology/kead670 | DOI Listing |
J Imaging Inform Med
January 2025
Computer Science Department, University of Geneva, Geneva, Switzerland.
Accurate wound segmentation is crucial for the precise diagnosis and treatment of various skin conditions through image analysis. In this paper, we introduce a novel dual attention U-Net model designed for precise wound segmentation. Our proposed architecture integrates two widely used deep learning models, VGG16 and U-Net, incorporating dual attention mechanisms to focus on relevant regions within the wound area.
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January 2025
Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard (Deemed University), M. B. Road, New Delhi 110062, India. Electronic address:
J Biomech
January 2025
Biorobotics and Biomechanics Lab, Department of Mechanical Engineering, University of Maine, Orono, 04469, ME, United States of America. Electronic address:
Interlimb coordination can be used as a metric to study the response of the neuromuscular system to mechanical perturbations and behavioral information. Behavioral information providing haptic feedback on thigh angle has been shown to increase stride length and consequently walking speed, but the effect of such feedback on limb coordination has not been determined. The current work investigates the effects of this feedback on lower-limb coordination and examines if such effects are dependent on the age of the walker.
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January 2025
Indiana University School of Optometry, Bloomington, Indiana.
Purpose: This study investigated how obstacle contrast altered gait behavior of healthy younger and older adults.
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Bone and Joint Health, Blizard Institute, Queen Mary University London, 4 Newark Street, London, E1 2AT, UK.
Post-surgical rehabilitation advice after ankle fracture surgery, particularly regarding weight-bearing, varies significantly, leading to patient frustration and inconsistent recovery outcomes. This study aimed to establish a consensus for ankle fracture rehabilitation advice and identify content and implementation options for future interventions through consultation with healthcare professionals (HCPs). This study was part of the weight-bearing in ankle fractures (WAX) trial, a multicentre, randomised controlled trial.
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