[This corrects the article DOI: 10.7759/cureus.50688.].
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http://dx.doi.org/10.7759/cureus.c149 | DOI Listing |
Semin Ophthalmol
March 2025
Department of Ophthalmology, Peking University People's Hospital, Beijing, China.
Purpose: To evaluate and contrast the effectiveness and safety of two conbercept treatment protocols-a three-dose treat-and-extend (3+T&E) regimen and a three-dose pro re nata (3+PRN) regimen-in Chinese patients diagnosed with neovascular age-related macular degeneration (nAMD).
Methods: Eligible patients, who had not undergone anti-VEGF intraocular injections within 3 months prior to enrollment, were randomly assigned to either the 3+T&E or 3+PRN regimen. The 3+T&E group received at least three monthly injections, with subsequent visit intervals extended based on disease activity assessment.
Background And Aims: Alzheimer's disease (AD) is a widespread neurodegenerative condition that has a growing impact on a global scale. This study aims to examine the relationship between cerebral blood flow (CBF) and the synaptic biomarker growth-associated protein 43 (GAP-43) through the utilization of arterial spin labeling (ASL). The research identified noteworthy correlations between cerebrospinal fluid (CSF) GAP-43 levels, CBF, and cognitive composite scores, especially among participants with mild cognitive impairment (MCI) who possess the APOE-ε4 gene.
View Article and Find Full Text PDFFront Neurosci
February 2025
Department of Urology, Huashan Hospital, Fudan University, Shanghai, China.
Background: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent condition in urology characterized by chronic pain. The pathogenesis of CP/CPPS remains unclear.
Methods: We enrolled 45 eligible CP/CPPS patients and 45 healthy volunteers.
Front Med (Lausanne)
February 2025
Department of Cataract Surgery, Oftalvist Alicante, Alicante, Spain.
Background: To evaluate refractive, visual, and patient-reported outcomes three months after bilateral implantation of a novel bi-aspheric, non-diffractive extended depth of focus (EDOF) intraocular lens (IOL) using PhaseRing technology to achieve good vision across distances with reduced dysphotopsia.
Methods: Twenty-two patients received bilateral Asqelio EDOF IOLs (AST VisionCare Inc.) and were evaluated 3 months post-surgery.
Anal Sci Adv
June 2025
BCSIR Laboratories Bangladesh Council of Scientific and Industrial Research (BCSIR) Dhaka Bangladesh.
The present study is to develop a cost-effective, non-destructive and rapid method for quantification of syringyl/guaiacyl (S/G) ratio content in non-wood lignin, which is based on FT-NIR spectroscopic data and chemometric modelling techniques. The S/G ratio in 22 non-wood lignins was determined by wet chemical method. Then the same samples were run with FT-NIR, and the spectroscopic data were pre-processed with Savitzky-Golay (S-G) on their 1st and 2nd derivatives.
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