To break through the limitations of the classical sine condition, a multi-field cosine condition (MCC) is proposed in this paper. Building on this condition, a design method for wide field-of-view (FOV) freeform aplanatic systems is also proposed. This design method ensures that the optical system meets the MCC by correcting the mapping relationships of rays that originate from different apertures on both the object and image sides of the optical system. Using this method, we have successfully designed a chromatic-aberration-free and unobstructed freeform off-axis reflective microscope objective that is characterized by a wide FOV, an extensive spectral working range, and an extended working distance. The objective, which comprises only three freeform mirrors, has a numerical aperture (NA) of 0.4, magnification of 20×, an FOV of 2 mm × 2 mm, and an extended working distance of up to 60 mm. The objective demonstrates imaging quality close to the diffraction limit across the visible band to the short-wave infrared band (0.4-3 µm). When compared with a transmission-type wide-field microscope objective with identical NA and magnification properties, the reflective microscope objective nearly triples the FOV.
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http://dx.doi.org/10.1364/OE.507749 | DOI Listing |
J Coll Physicians Surg Pak
January 2025
Department of Microbiology, Armed Forces Institute of Pathology / National University of Medical Sciences, Rawalpindi, Pakistan.
Objective: To evaluate Chicago Sky Blue (CSB) stain, Calcofluor white (CW) stain, and Potassium Hydroxide (KOH) mount for rapid diagnosis of dermatomycosis, using fungal culture as the gold standard.
Study Design: Cross-sectional analytical study. Place and Duration of the Study: This study was conducted in the Department of Microbiology, Armed Forces Institute of Pathology / National University of Medical Sciences, Rawalpindi, Pakistan, from July 2023 to February 2024.
BMC Res Notes
January 2025
Helen Keller International, New York, USA.
Objective: Sierra Leone, a country where onchocerciasis is endemic in 14 of the 16 districts, was the focus of our investigation. Despite 17 rounds of annual ivermectin treatment since 2005, a report circulated by a local politician indicated an increase in cases of suspected onchocerciasis-related vision impairment in two villages (Mangobo and Petifu) in Tonkolili district. In response, the National Neglected Tropical Disease Program conducted a comprehensive investigation.
View Article and Find Full Text PDFBackground: This study aimed to explore the clinical and pathological features of patients with diabetic kidney disease (DKD), with and without non-diabetic kidney disease (NDKD), through a retrospective analysis. The objective was to provide clinical insights for accurate identification.
Methods: A retrospective analysis of 235 patients admitted to the Department of Nephrology at Hangzhou Hospital of Traditional Chinese Medicine was conducted between July 2014 and December 2022.
Arch Oral Biol
January 2025
State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China. Electronic address:
Objectives: The present study aimed to explore the inhibitory effect of taxifolin (TAX) on Streptococcus mutans (S. mutans) in vitro and evaluated the anti-caries efficacy of TAX in vivo.
Design: The anti-microbial and anti-biofilm properties of TAX were examined on the S.
Oper Neurosurg (Hagerstown)
February 2025
Rhoton Neurosurgery and Otolaryngology Surgical Anatomy Program, Mayo Clinic, Rochester , Minnesota , USA.
Background And Objectives: The coexistence of complete carotico-clinoid bridge (CCB), an ossification between the anterior (ACP) and the middle clinoid (MCP), and an interclinoidal osseous bridge (ICB), between the ACP and the posterior clinoid (PCP), represents an uncommonly reported anatomic variant. If not adequately recognized, osseous bridges may complicate open or endoscopic surgery, along with the pneumatization of the ACP, especially when performing anterior or middle clinoidectomies.
Methods: According to Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Reviews guidelines, a systematic scoping review was conducted up to June 5, 2023.
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