AI Article Synopsis
- The study focused on COVID-19 patients in the Philippines who have existing coronary artery disease (CAD) or heart failure (HF) to analyze their health outcomes compared to those without these conditions.
- Data from the Philippine CORONA Study revealed that patients with CAD/HF experienced more severe COVID-19 symptoms, higher rates of mortality (especially related to cardiac issues), longer hospital stays, and increased respiratory failure.
- Findings indicate that even after considering other health factors, having CAD or HF significantly raised the odds of dying from cardiac causes in COVID-19 patients.
Article Abstract
Background: Patients with coronavirus disease 2019 (COVID-19) and coronary artery disease (CAD) or heart failure (HF) are more likely to have poor outcomes. This study aimed to determine the characteristics and outcomes of COVID-19 patients with CAD/HF across various institutions in the Philippines.
Methods: We utilized the data from the Philippine CORONA Study and compared the outcomes of admitted COVID-19 patients with CAD/HF versus those without. The Student's t test, Mann-Whitney U test, binary logistic regression and multivariate regression analysis were utilized. Odds ratios (OR) and Kaplan-Meier curves were generated.
Results: We included a total of 512 patients with COVID-19 had CAD/HF and 10,369 were without. CAD/HF was significantly associated with COVID severity, all-cause mortality, death from cardiac causes, respiratory failure, and prolonged hospitalization. After adjusting for confounders, the presence of CAD/HF was still associated with death from a cardiac cause (OR 2.22, 95% CI 1.49-3.3, p < 0.01).
Conclusions: The presence of CAD or HF was significantly associated with severity of COVID disease, all-cause mortality, death from cardiac causes, respiratory failure, and prolonged hospitalization.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10768280 | PMC |
| http://dx.doi.org/10.1186/s13104-023-06677-5 | DOI Listing |
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