Central granular cell odontogenic tumor (CGCOT) is a rare, benign odontogenic tumor resulting from the jaw bone, especially the mandible or maxilla. It affects women of middle age and usually occurs as a painless swelling of the mandibular premolar-molar area. CGCOT is characterized by the presence of granular cells, which are large, eosinophilic, granular-looking cells found in the tumor tissue. We report an unusual CGCOT in a 38-year-old male patient's mandibular region. We also describe the clinical, radiological, and pathological characteristics along with the immunohistochemical investigation of the tumor.
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http://dx.doi.org/10.7759/cureus.49914 | DOI Listing |
J Clin Med
December 2024
Department of Oral and Maxillofacial Diagnostic Sciences, College of Dentistry, Taibah University, Medina 41477, Saudi Arabia.
To determine the prevalence of oral and maxillofacial lesions among patients at King Abdulaziz University from January 2016 to December 2022. : This cross-sectional observational study included patients diagnosed with oral and maxillofacial intra-bony lesions based on radiological findings and confirmed by histopathological examination. The lesions were classified according to the fourth edition of the World Health Organization Classification of Head and Neck Tumors.
View Article and Find Full Text PDFJ Vet Med Sci
January 2025
Laboratory of Veterinary Pathology, School of Veterinary Medicine, Azabu University.
This report describes an atypical case of canine acanthomatous ameloblastoma (CAA) with mucinous glandular differentiation in a 12-year-old male Chihuahua with a right mandibular mass. Initially diagnosed as CAA by biopsy, computed tomography revealed bone lysis, prompting surgical excision. Histological examination showed lobular growth with two distinct neoplastic cell populations: typical CAA-like cells and a minor glandular structure population.
View Article and Find Full Text PDFInt J Surg Case Rep
January 2025
Department of Oral and Maxillofacial Surgery, School of Dentistry, Azad University of Medical Sciences, Shiraz, Iran.
Introduction And Importance: The most common type of odontogenic tumor is odontoma. Cases with at least one dimension (sagittal, axial, or coronal) ≥30 mm were categorized as giant odontomas. This study aimed to provide a scoping review of giant odontoma and present a case report.
View Article and Find Full Text PDFJ Zhejiang Univ Sci B
December 2024
Department of Oral Pathology, Peking University School and Hospital of Stomatology / National Center of Stomatology / National Clinical Research Center for Oral Diseases / National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing 100081, China.
In light of the lack of reliable molecular markers for odontogenic myxoma (OM), the detection of copy number variation (CNV) may present a more objective method for assessing ambiguous cases. In this study, we employed multiregional microdissection sequencing to integrate morphological features with genomic profiling. This allowed us to reveal the CNV profiles of OM and compare them with dental papilla (DP), dental follicle (DF), and odontogenic fibroma (OF) tissues.
View Article and Find Full Text PDFOral Maxillofac Surg
December 2024
Department of Oral and Maxillofacial Surgery, Faculty of Dental Sciences Institute of Medical Sciences, Banaras Hindu University, Varanasi Uttar Pradesh, 221001, India.
Purpose: Ameloblastoma is a benign tumor originating from odontogenic epithelium with a global incidence of about 0.5 cases per million persons per year. The overall recurrence rate of ameloblastomas range from 55% -90%.
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