Anesthetic management of parturients with achondroplasia: a case series.

Proc (Bayl Univ Med Cent)

Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, USA.

Published: December 2023

AI Article Synopsis

  • Achondroplasia is the most common form of dwarfism, and cesarean deliveries for these patients often require special anesthetic considerations due to cephalopelvic disproportion.
  • A study analyzed data from female patients with achondroplasia who delivered in a health system over a period of more than 22 years, identifying seven patients with twelve cesarean deliveries.
  • The findings suggest that while general anesthesia has been traditionally favored due to anatomical challenges, neuraxial anesthesia can be safely and effectively used in selected achondroplastic patients with careful management of local anesthetic dosages.

Article Abstract

Background: Achondroplasia is the most common form of dwarfism, and cesarean delivery is often required in parturients with achondroplasia due to cephalopelvic disproportion. Given the challenges for both regional and general anesthetic techniques, there is no consensus on the optimal anesthetic management for cesarean delivery in these patients.

Method: A search of our electronic medical records for all female patients who had a diagnosis of achondroplasia and had a delivery in our health system from January 1, 2001 through June 16, 2023 was performed. Institutional review board exemption was obtained.

Results: We identified seven achondroplastic patients with 12 cesarean deliveries and described their anesthetic management during labor and delivery.

Conclusion: Despite the historical preference of general anesthesia in achondroplastic patients due to concerns of unpredictable spinal anatomy and unreliable local anesthetic spread, neuraxial anesthesia was successfully utilized in achondroplastic parturients and is a viable option in carefully selected patients. Reduction of intrathecal local anesthetic dose that minimizes the risk of high spinal and emergent intubation, as well as a titratable neuraxial technique, can be effective in this patient population.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10761160PMC
http://dx.doi.org/10.1080/08998280.2023.2261084DOI Listing

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