infection is a prevalent global infection associated with several complications such as peptic ulcer, upper gastrointestinal bleeding, and stomach cancer. An imbalance in the gut microbiota composition or the relationship between the microbiota and the host may be implicated in the infection. To investigate this, we studied the intestinal microbiota of 50 newly infected adolescents with compared with 50 age-matched and sex-matched healthy controls. The gut microbiota composition was assessed using real-time polymerase chain reaction (RT-PCR), and the fecal bacterial diversity and composition were compared between groups. Our findings revealed that and spp. were significantly higher in the patient group compared to the control group. Additionally, lower counts of eubacteria, , were observed in the gut of adolescents with Conversely, adolescents with infection had non-significantly higher counts of Multiple logistic regression analysis revealed that a greater abundance of and , a higher prevalence of , and a lower abundance of were predictive of infection. Overall, our results suggest that infection is associated with changes in fecal microbiome composition.
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