AI Article Synopsis

  • Rising living standards have led to an increase in liver injuries, highlighting the limitations of traditional diagnostic methods in providing early and accurate detection.
  • Fluorescent probes using various fluorophores and nanomaterials show promise in medical research due to their high specificity and non-invasive nature, enabling better identification of liver injury biomarkers.
  • The review examines recent advancements in fluorescent probes, outlines liver injury biomarkers, discusses their structures and response mechanisms, and suggests future improvements for better diagnosis and assessment of liver injuries.

Article Abstract

With the increase in people's living standards, the number of patients suffering from liver injury keeps on increasing. Traditional diagnostic methods can no longer meet the needs of early and accurate diagnosis due to their limitations in application. However, fluorescent probes based on different fluorophores and nanomaterials have been gradually lighting up medical research due to their unique properties, such as high specificity and non-invasiveness. In addition, accurate identification of the different types of liver injury biomarkers can significantly improve the level of early diagnosis. Therefore, this review reviews the fluorescent probes used in the detection of biomarkers of liver injury over recent years and briefly summarizes the corresponding biomarkers of different types of liver injury. Impressively, this review also lists the structures and the response mechanisms of the different probes, and concludes with an outlook, suggesting directions in which improvements can be made. Finally, we hope that this review will contribute to the further development of fluorescent probes for the early diagnosis and assessment of liver injury.

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Source
http://dx.doi.org/10.1039/d3an01631eDOI Listing

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