The self-prioritization effect suggests that self-relevant information has a processing advantage over information that is not directly associated with the self. In consequence, reaction times are faster and accuracy rates higher when reacting to self-associated stimuli rather than to other-related stimuli (Sui et al., Journal of Experimental Psychology: Human Perception and Performance 38:1105-1117, 2012). This spurs the assumption that self-associated action-effects should also be perceived earlier than other-related outcomes. One way to measure this is temporal binding. Previous research indeed showed that the perceived temporal interval between actions and self-associated outcomes was reduced compared to friend- and other-associated outcomes. However, the employed method (interval estimations) and several experimental design choices make it impossible to discern whether the perceived shortening of the interval between a keypress and a self-relevant outcome is due to a perceptual shift of the action or of the action-effect or both. Thus, we conducted four experiments to assess whether temporal binding can indeed be modulated by self-relevance and if so where this perceptual bias is located. The results did not support stronger temporal binding for self- vs other-related action-effects. We discuss these results against the backdrop of the attentional basis of self-prioritization and propose directions for future research.
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http://dx.doi.org/10.1007/s00426-023-01906-9 | DOI Listing |
JDS Commun
January 2025
Department of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, WI 53706.
Lipases such as patatin-like phospholipase domain-containing protein 3 (PNPLA3) exist in multiple tissue types. In subcutaneous adipose tissue, PNPLA3 was not altered during the periparturient period. Conversely, strong associations between liver PNPLA3 and liver triglyceride content peripartum were identified and confirmed to be causative using knockdown approaches in a primary bovine hepatocyte model.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Pharmacology & Toxicology, The University of Texas Medical Branch, Galveston, Texas, United States of America.
Severe acute respiratory syndrome coronavirus-1 (SARS-CoV-1) and -2 (SARS-CoV-2) are beta-coronaviruses (β-CoVs) that have caused significant morbidity and mortality worldwide. Therefore, a better understanding of host responses to β-CoVs would provide insights into the pathogenesis of these viruses to identify potential targets for medical countermeasures. In this study, our objective is to use a systems biology approach to explore the magnitude and scope of innate immune responses triggered by SARS-CoV-1 and -2 infection over time in pathologically relevant human lung epithelial cells (Calu-3/2B4 cells).
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January 2025
Natural Products Research Center, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, P.R. China. Electronic address:
As a promising therapeutic approach, the RNA editing process can correct pathogenic mutations and is reversible and tunable, without permanently altering the genome. RNA editing mediated by human ADAR proteins offers unique advantages, including high specificity and low immunogenicity. Compared to CRISPR-based gene editing techniques, RNA editing events are temporary, which can reduce the risk of long-term unintended side effects, making off-target edits less concerning than DNA-targeting methods.
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January 2025
Federal Institute for Materials Research and Testing (BAM), Division 1.1 - Inorganic Trace Analysis, Richard-Willstätter-Straße 11, Berlin 12489, Germany. Electronic address:
Organotin (OT) compounds, while crucial in many industrial applications, pose substantial risks to the environment and human health. The toxicity and environmental behaviour of OTs depend on their chemical form, i.e.
View Article and Find Full Text PDFHear Res
December 2024
Leibniz Institute for Neurobiology, Research Group Comparative Neuroscience, Magdeburg, Germany; Department of Psychology, Lancaster University, Lancaster, UK.
Adaptation is the attenuation of a neuronal response when a stimulus is repeatedly presented. The phenomenon has been linked to sensory memory, but its exact neuronal mechanisms are under debate. One defining feature of adaptation is its lifetime, that is, the timespan over which the attenuating effect of previous stimulation persists.
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