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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10764006 | PMC |
| http://dx.doi.org/10.7554/eLife.95782 | DOI Listing |
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Similar Publications
Scleraxis-lineage cells are required for correct muscle patterning.
Development
May 2023
Laboratory of Animal Regeneration Systemology, Department of Life Sciences, School of Agriculture, Meiji University, Kanagawa, 214-8571, Japan.
Article Synopsis
- - The study investigates the role of scleraxis (Scx)-lineage cells in the development and attachment of skeletal muscles in mouse embryos through targeted cell ablation techniques.
- - Results showed that the absence of Scx-lineage cells led to significant changes in muscle shape and improper attachment sites, particularly in forelimb and limb girdle muscles.
- - The findings highlight that while Scx-lineage cells are crucial for muscle attachment and morphology after myofiber fusion, they do not influence the initial separation of myoblasts, indicating important interactions between muscle and connective tissue in development.
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