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| http://dx.doi.org/10.1038/s41591-023-02646-4 | DOI Listing |
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Drug Development.
Alzheimers Dement
December 2024
The George Institute for Global Health, University of New South Wales, Imperial College London, Sydney, NSW, Australia.
Background: Recent growth in the functionality and use of technology has prompted an increased interest in the potential for remote or decentralised clinical trials in dementia. There are many potential benefits associated with decentralised medication trials, but the field is currently lacking specific recommendations for their delivery in the dementia field.
Method: A modified Delphi method engaged a panel with substantial expertise in dementia trial design and delivery and backgrounds that included neurology, psychiatry, pharmacology and psychology, to develop recommendations for the conduct of decentralised medication trials in dementia prevention.
"From the territorial grounds": an interview with Weibe Tapeba, secretary of Indigenous Health at the Ministry of Health.
Cien Saude Colet
December 2024
Instituto Leônidas & Maria Deane - Fiocruz Amazônia. Manaus AM Brasil.
In this interview, Weibe Tapeba, secretary of Indigenous Health at the Ministry of Health in the Lula Government, discusses the process of reorganizing the Secretariat of Indigenous Health (SESAI) and Indigenous protagonism in the new administration. Among the points highlighted by the interviewee are the assessment of the Indigenous health scenario within the current political context of the Ministry of Health, dialogues with Indigenous movement organizations, as well as collaboration with research and educational institutions. The interview highlights the importance of developing strategies aimed at restructuring SESAI and improving Indigenous health public policy in Brazil through extensive coordination, involving planning, management, funding, and Indigenous social participation with Social Control.
View Article and Find Full Text PDFMeasuring Improvement Capabilities in a Health System: Findings From a Content Validity Study.
Am J Med Qual
January 2025
Strategy & Operations, Curation Health, Annapolis, MD.
Measurable improvements in the American Healthcare System have been elusive. To understand why, a survey measuring improvement capabilities in a health system was developed from a 2002 tool that measured an outdated quality improvement methodology. That survey was tested for content validity and achieved an overall representativeness content validity index of 87.
View Article and Find Full Text PDFLiving with Pediatric Coeliac Disease: Lessons for Health Service Delivery.
Dig Dis Sci
January 2025
Department of Paediatric Gastroenterology, Hepatology and Liver Transplant, Queensland Children's Hospital, Graham St, South Brisbane, 4101, Australia.
Background: Coeliac Disease (CD) affects up to 1.4% of children worldwide, with a rising global incidence. A less typical clinical presentation and the need for a life-long gluten exclusion diet raise challenges for diagnosis, management, and healthcare delivery with considerable impacts for CD patients and families as well as clinical services.
View Article and Find Full Text PDFEnhancing security and efficiency in Mobile Ad Hoc Networks using a hybrid deep learning model for flooding attack detection.
Sci Rep
January 2025
North Carolina School of Science and Mathematics, Durham, NC, 27705, USA.
Mobile Ad Hoc Networks (MANETs) are increasingly replacing conventional communication systems due to their decentralized and dynamic nature. However, their wireless architecture makes them highly vulnerable to flooding attacks, which can disrupt communication, deplete energy resources, and degrade network performance. This study presents a novel hybrid deep learning approach integrating Convolutional Neural Networks (CNN) with Long Short-Term Memory (LSTM) and Gated Recurrent Unit (GRU) architectures to effectively detect and mitigate flooding attacks in MANETs.
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