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Circulating large extracellular vesicles as diagnostic biomarkers of indeterminate thyroid nodules: multi-platform omics analysis.
BJS Open
December 2024
Institute of Cardiovascular Sciences, University College London, London, UK.
Background: While most thyroid nodules are benign, 7-15% are malignant. Patients with indeterminate thyroid nodules (specifically Bethesda IV/Thy3f) often undergo diagnostic hemithyroidectomy to reach a diagnosis on final histology. The aim of this study was to assess the feasibility of circulating large extracellular vesicles as diagnostic biomarkers in patients presenting with Thy3f thyroid nodules.
View Article and Find Full Text PDFIncipient and subclinical tuberculosis: a narrative review.
Monaldi Arch Chest Dis
January 2025
Department of Pulmonary Medicine, Indira Gandhi Medical College, Shimla, Himachal Pradesh.
Mycobacterium tuberculosis has been known to infect humans for eons. It is an airborne infectious disease transmitted through droplet nuclei of 1 to 5 µm in diameter. Historically, tuberculosis (TB) was considered a distinct condition characterized by TB infection and active TB disease.
View Article and Find Full Text PDFHepatic Perivascular Epithelioid Cell Tumor (PEComa): A Case Report.
Cureus
December 2024
Pathology and Laboratory Medicine, Saint Michael's Medical Center, Newark, USA.
Perivascular epithelioid cell tumors (PEComas) are a rare group of mesenchymal neoplasms composed of perivascular epithelioid cells. While commonly found in the kidney, uterus, and soft tissues, PEComas of the liver are exceedingly rare. We present a case of a PEComa incidentally discovered in a 73-year-old female patient undergoing evaluation for abdominal pain.
View Article and Find Full Text PDFSolid pseudopapillary epithelial neoplasm of the pancreas with liver metastasis.
BMJ Case Rep
January 2025
Department of General Surgery, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, Maharashtra, India.
A girl in early adolescence presented with complaints of abdominal pain lasting for 4 months, along with a palpable lump in the epigastric region. A CT scan revealed a large solid-cystic mass lesion measuring 9.5×10.
View Article and Find Full Text PDFPeripheral blood immune cell dynamics associate with growth of incidental indeterminate pulmonary nodules.
Respir Med
January 2025
Department of Respiratory and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address:
Objectives: Previous studies suggest peripheral blood immune cells associate with the progression and prognosis of lung cancer. The main purpose of this study was to explore the association of peripheral immune cell and its dynamics with the growth of pulmonary nodules.
Materials And Method: Of 9280 subjects whom had blood cell counts and chest CT scan in health check-up, 1068 participants were enrolled with the incidental pulmonary nodules of above 5mm in diameter and subsequently followed up for 2 years.
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