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Envenoming by a captive Inland Taipan, Oxyuranus microlepidotus (McCoy, 1879), Elapidae. A case report, observations on clinical efficacy of expired antivenom and review of O. microlepidotus envenoming.
Toxicon
December 2024
University of South Florida, Department of Emergency Medicine, Tampa, FL, USA; Florida Poison Information Center, Tampa, FL, USA.
The clinical evolution and management of a 22-yr-old male envenomed by a captive female inland taipan, Oxyuranus microlepidotus (McCoy, 1879), Elapidae, at a public educational reptile exhibit (Florida, USA) is reported. The patient was bitten (quick 'bite and release') in the right hand between digits #3 and 4 while performing captive maintenance. The victim did not attempt any first aid, but urgently presented to the local hospital within 25 mins post-bite.
View Article and Find Full Text PDFRecurrent Subdural and Epidural Hematomas: A Case Report of Complications Following Craniotomy and Middle Meningeal Artery Embolization.
Cureus
November 2024
Internal Medicine, UChicago Medicine AdventHealth, La Grange, USA.
This report presents a 76-year-old male patient who developed indolent right-sided upper and lower extremity weakness and low back pain following a fall that resulted in no trauma and was not prompted by syncope or vertigo. Imaging revealed a chronic subdural hematoma (cSDH) with midline shift, for which the patient underwent craniotomy and middle meningeal artery (MMA) embolization. Despite initial intervention, the patient experienced rare and severe complications, including the recurrence of a subdural hematoma (SDH), the development of an epidural hematoma, and frontal lobe herniation.
View Article and Find Full Text PDFLong-term survival in a patient with Li-Fraumeni syndrome-associated giant cell glioblastoma treated with nivolumab: illustrative case.
J Neurosurg Case Lessons
November 2024
Department of Neurological Surgery, Corewell Health, Grand Rapids, Michigan.
Background: Li-Fraumeni syndrome (LFS) is characterized by p53 germline mutations and a high predisposition to cancers including glioblastoma (GBM), the most common and aggressive primary malignant brain tumor in adults. Despite current therapies, the 5-year survival rate is 5%-10%. The authors report a case with a durable long-term response to immunotherapy with checkpoint inhibition in a patient with LFS-associated GBM.
View Article and Find Full Text PDFVirtual neurology survey: Factors influencing virtual care use among Ontario neurologists.
SAGE Open Med
November 2024
Department of Medicine, University of Toronto, Toronto, ON, Canada.
Background And Objectives: Current virtual care guidance lacks specialty-specific considerations. Neurological care is unique due to its reliance on physical examination and complex patient population. Our aim was to determine which factors impact virtual care suitability in neurology, virtual care adoption patterns, and satisfaction with virtual care among neurologists.
View Article and Find Full Text PDFArtificial intelligence driven clustering of blood pressure profiles reveals frailty in orthostatic hypertension.
Exp Physiol
November 2024
Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Gravity, an invisible but constant force , challenges the regulation of blood pressure when transitioning between postures. As physiological reserve diminishes with age, individuals grow more susceptible to such stressors over time, risking inadequate haemodynamic control observed in orthostatic hypotension. This prevalent condition is characterized by drops in blood pressure upon standing; however, the contrary phenomenon of blood pressure rises has recently piqued interest.
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