This chapter presents a practical guide for conducting sentiment analysis using Natural Language Processing (NLP) techniques in the domain of tick-borne disease text. The aim is to demonstrate the process of how the presence of bias in the discourse surrounding chronic manifestations of the disease can be evaluated. The goal is to use a dataset of 5643 abstracts collected from scientific journals on the topic of chronic Lyme disease to demonstrate using Python, the steps for conducting sentiment analysis using pretrained language models and the process of validating the preliminary results using both interpretable machine learning tools, as well as a novel methodology of leveraging emerging state-of-the-art large language models like ChatGPT. This serves as a useful resource for researchers and practitioners interested in using NLP techniques for sentiment analysis in the medical domain.
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