AI Article Synopsis

  • Pancreatic cancer is known for its poor survival rates, improving slowly compared to other types of cancer.
  • Treatment typically involves a combination of chemotherapy, surgery, and radiotherapy, with a focus on how the cancer spreads locally.
  • Recent advancements in treatment strategies prompt a need for further research to explore new ways to manage and improve outcomes for pancreatic cancer patients.

Article Abstract

Pancreatic cancer remains among the malignancies with the worst outcomes. Survival has been improving, but at a slower rate than other cancers. Multimodal treatment, including chemotherapy, surgical resection, and radiotherapy, has been under investigation for many years. Because of the anatomical characteristics of the pancreas, more emphasis on treatment selection has been placed on local extension into major vessels. Recently, the development of more effective treatment regimens has opened up new treatment strategies, but urgent research questions have also become apparent. This review outlines the current management of pancreatic cancer, and the recent advances in its treatment. The review discusses future treatment pathways aimed at integrating novel findings of translational and clinical research.

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Source
http://dx.doi.org/10.1136/bmj-2022-073995DOI Listing

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