Prevalence of co-infection with human papillomavirus and Chlamydia trachomatis and risk factors associated with cervical cancer in Congolese women.

Microbes Infect

Team of Virology Oncology and Biotechnologies Laboratory of Virology, Oncology, Biosciences, Environment and New Energy, Faculty of Science and Technology, Mohammedia, Hassan II University of Casablanca, Casablanca, Morocco. Electronic address:

Published: March 2024

AI Article Synopsis

  • HPV is a common virus linked to cervical cancer, especially in developing countries, and Chlamydia trachomatis (CT) is a significant factor in this relationship.
  • In a study of 131 cervical samples, 17.5% were HPV-only positive, 7.6% were CT-only, and 9.9% showed co-infection of both.
  • Risky sexual behaviors and cytology status were identified as key factors related to HPV/CT co-infection, highlighting the need for increased awareness and protective measures against cervical cancer.

Article Abstract

The human papillomavirus (HPV) is one of the most frequently diagnosed viruses in developing countries. Chlamydia trachomatis (CT) is an important cofactor in HPV-induced cervical cancer. Cervico-uterine smears were taken for cytology, and a total of 131 samples were analysed. HPV prevalence and CT were detected using specific primers (L1 gene and omp-1 gene). 23 (17.5 %) HPV-only samples were detected, CT-only positives were 10 (7.6 %). And HPV/CT co-infection was 13 (9.9 %). Identified risk factors associated with HPV/CT co-infection were risky sexual behaviour and cytology status. The prevalence of HPV and CT and their co-infection rates being high in our study population, may be an indicator of cervical cancer risk. Consequently, there is an urgent need to raise awareness and take appropriate precautions.

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Source
http://dx.doi.org/10.1016/j.micinf.2023.105287DOI Listing

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