This video abstract delves into the expanded definition of diabetic striatopathy, linked initially to hyperglycemia-induced choreoballism and striatal hyperintensity on magnetic resonance imaging, but now recognized to encompass a broader range of acute onset, non-choreoballistic movement disorders in diabetes mellitus, including tremors, hemifacial spasm, parkinsonism, different types of myoclonus, dystonia, restless leg syndrome, ataxia, and dyskinesias. We report the case of a 45-year-old female patient with type-2 diabetes mellitus who developed propriospinal myoclonus, characterized by painless, involuntary jerky movements of the bilateral lower limbs in a supine position after admission for suspected rhino-orbital mucormycosis. The abnormal movements resolved entirely following the control of her blood glucose levels, suggesting a direct correlation between hyperglycemia and the clinical picture. This case highlights the importance of considering a wide range of differential diagnoses for abnormal lower limb movements in diabetic patients, emphasizing the need for accurate identification of movement semiology, routine bedside capillary blood glucose checks, and prompt hyperglycemia management to resolve such movement disorders effectively.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10756153PMC
http://dx.doi.org/10.5334/tohm.850DOI Listing

Publication Analysis

Top Keywords

diabetic striatopathy
8
propriospinal myoclonus
8
movement disorders
8
diabetes mellitus
8
blood glucose
8
expanding spectrum
4
spectrum diabetic
4
striatopathy insights
4
insights case
4
case hyperglycemia-induced
4

Similar Publications

Diabetes mellitus is one of the most frequent endocrinopathies in the medical routine, appearing across different specialties. Although neurological involvement in the form of peripheral neuropathy is the most recurrent form acknowledged by physicians, the spectrum of neurological involvement can be more diverse. Here, we present a case of diabetic striatopathy, a rare neurological manifestation of diabetes mellitus with poor metabolic control, in a patient whose epidemiological group was not classically.

View Article and Find Full Text PDF

Background: Diabetic striatopathy (DS) is a rare disorder characterized by clinical manifestations of hemichorea, non-ketotic hyperglycemia, and high signal on T1-weighted MRI or high density on CT scan in basal ganglia, typically associated with poor glycemic control.

Objective: This study aimed to analyze clinical characteristics of patients with diabetic striatopathy to raise awareness amongst physicians, especially endocrinologists, about this rare neurological manifestation in patients with diabetes.

Methods: We retrospectively analyzed the data on clinical presentations, laboratory workups, and cranial CT and MRI of six patients with DS who were admitted to our hospital from October 2013 to June 2022.

View Article and Find Full Text PDF

Chorea in Hemodialysis Patients: Report of Two Cases.

Int J Nephrol Renovasc Dis

November 2024

Department of Nephrology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, 210006, People's Republic of China.

Article Synopsis
  • - Chorea, which is characterized by involuntary limb movements, is rare in patients on maintenance dialysis but significantly impacts their quality of life, with limited prior documentation on the condition.
  • - Two hemodialysis patients with end-stage renal disease experienced worsening involuntary movements; one was treated for diabetic striatopathy, while the other for uremic metabolic encephalopathy, both with subsequent symptom improvement.
  • - The cases highlight that choreiform movements in hemodialysis patients can arise from different causes, indicating a need for careful diagnosis and treatment in the early stages of dialysis.
View Article and Find Full Text PDF

Movement disorders associated with diabetes mellitus (DM) are rare. The diagnosis of diabetic striatopathy (DS) is based on the presence of a triad characterized by hyperglycemia, hemiballismus/chorea, and hypersignal of the basal ganglia on T1-weighted MRI. In most cases, treatment involves glycemic control.

View Article and Find Full Text PDF

Nonketotic hyperglycemia-induced hemichorea is a rare condition of type 2 diabetes. It is characterized by hyperglycemia with the symptom traced to the basal ganglion like hemichorea or hemiballism, with the hyperintensity within basal ganglion presented in computed tomography (CT) or hyper signal in T1-weighted magnetic resonance image (MRI). It was also confirmed with a relatively better prognosis in that the symptoms of these patients could be relieved after the alleviation of hyperglycemia.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!