Mediation analysis investigates the covariation of variables in a population of interest. In contrast, the resolution level of psychological theory, at its core, aims to reach all the way to the behaviors, mental processes, and relationships of individual persons. It would be a logical error to presume that the population-level pattern of behavior revealed by a mediation analysis directly describes all, or even many, individual members of the population. Instead, to reconcile collective covariation with theoretical claims about individual behavior, one needs to look beyond abstract aggregate trends. Taking data quality as a given and a mediation model's estimated parameters as accurate population-level depictions, what can one say about the number of people properly described by the linkages in that mediation analysis? How many individuals are exceptions to that pattern or pathway? How can we bridge the gap between psychological theory and analytic method? We provide a simple framework for understanding how many people actually align with the pattern of relationships revealed by a population-level mediation. Additionally, for those individuals who are exceptions to that pattern, we tabulate how many people mismatch which features of the mediation pattern. Consistent with the person-oriented research paradigm, understanding the distribution of alignment and mismatches goes beyond the realm of traditional variable-level mediation analysis. Yet, such a tabulation is key to designing potential interventions. It provides the basis for predicting how many people stand to either benefit from, or be disadvantaged by, which type of intervention.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.3758/s13428-023-02298-9 | DOI Listing |
Alzheimers Dement
December 2024
Innovation Center for Neurological Disorders, Xuanwu Hospital, Capital Medical University, Beijing, China;, Beijing, China.
Background: Individuals with type 2 diabetes mellitus (T2DM) face an increased risk of dementia. Recent discoveries indicate that SGLT2 inhibitors, a newer class of anti-diabetic medication, exhibit beneficial metabolic effects beyond glucose control, offering a potential avenue for mitigating the risk of Alzheimer's disease (AD). However, limited evidence exists regarding whether the use of SGLT2 inhibitors effectively reduces the risk of AD.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Hospital Alemão Oswaldo Cruz, São Paulo, São Paulo, Brazil.
Background: People with dementia (PWD) have several unmet needs during the syndrome progression. More unmet needs are related to worse outcomes, such as hospitalizations, injuries, and death. The caregiving burden has been related to more PWD unmet needs.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Murdoch University, Perth, Western Australia, Australia.
Background: Research on cognitive reserve (CR) in individuals aged 80 years old and above has resulted in inconsistent findings, mostly showing a relationship with baseline cognitive abilities but not follow up assessments. The effects of amyloid burden on the relationship between CR, cognitive decline and dementia in oldest old warrants further study in the presence of APOE e4. We hypothesised that CR in oldest old (≥80 yrs old) adults will result in different trajectories, depending on being amyloid PET positive or negative.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Yonsei University, Wonju, Gangwon-do, Korea, Republic of (South).
Background: Exercise or cognitive interventions have already been sufficiently provided to the elderly, and their effectiveness has been proven. However, interventions in the context of promoting social interaction have not been well-implemented for the elderly, and few studies have considered the effectiveness of interaction mediation for the elderly. This study therefore sought to examine the effectiveness of interactive interventions by examining studies that provide interventions focusing on social interactions.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Yonsei University, Wonju, Gangwon-do, Korea, Republic of (South).
Background: Dementia and visual impairment are both associated with reduced mobility and impaired functioning in activities of daily living (ADL) and instrumental activities of daily living (IADL). Cognitive deficits in older adults have more difficulties in performing daily tasks, increase the risk of fear of participation and may lead to injury (e.g.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!