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Pre- and post-polyphenol intake and ovarian cancer survival: evidence from a prospective cohort study.

Eur J Nutr

November 2024

Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.

Purpose: Although (poly)phenols have shown potential in anti-cancer activities, their impact on improving ovarian cancer (OC) survival remains unknown. Therefore, we aim to first investigate the association between dietary polyphenol intake and OC survival, providing valuable insights into potential interventions.

Methods: The prospective cohort recruited 560 patients with OC to assess the associations of polyphenol intake, not only pre- and post-diagnosis but also the change from pre- to post-diagnosis with OC survival.

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Background & Aims: Smell and taste changes are frequently reported bothersome treatment symptoms during treatment for childhood cancer and assumed to influence outcomes such as food intake. Since nutritional status of children with cancer is already vulnerable, any detrimental effects on food intake should be prevented. Therefore, understanding the exact relationship between chemosensory changes and dietary intake, eating behavior, and other domains such as health-related quality of life (HRQoL), is important for improving outcomes.

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Article Synopsis
  • - The study investigated the links between diet quality, as measured by the Healthy Eating Index-2020 (HEI-2020), and survival rates in ovarian cancer patients over a follow-up period until February 2023.
  • - It involved 1082 ovarian cancer patients aged 18-79, assessing their dietary habits before and after their diagnosis using a validated food questionnaire.
  • - Results indicated that higher diet quality scores led to better overall survival rates, while a decline in diet quality after diagnosis was linked to worse survival outcomes.
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