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Is there a relationship between CSF Interleukin 34 Level and clinicoradiological activity and IgG index in patients with MS?
Mult Scler Relat Disord
December 2024
Sivas Cumhuriyet University, Faculty of Medicine, Department of Neurology, Sivas, Turkey.
Article Synopsis
- Multiple sclerosis (MS) is an autoimmune disease whose mechanisms are being studied to improve prognosis and treatment options, focusing on Interleukin 34 (IL-34) for its potential role in MS activity.
- A study with 52 MS patients assessed CSF IL-34 levels over a year, comparing those with clinical/radiological activity to those without, and to a control group.
- Findings showed higher IL-34 levels in MS patients than controls, but no significant correlation with disease activity, suggesting IL-34 may be an important biomarker for MS pathogenesis despite not being linked to clinical symptoms.
Mesenteric inflammatory pseudotumor: A rare case report and review of the literature.
Radiol Case Rep
November 2024
Department of Pathology, Ibn Sina Hospital, Faculty of medicine and pharmacy, Mohammed V University, Rabat, Morocco.
Inflammatory pseudotumor (IP) is a rare type of benign tumor. Although initially identified in the lung, it has now been identified in a number of somatic and visceral sites, but mesenteric presentation is uncommon and has a variable clinical presentation. As inflammatory pseudotumor mimic malignancy both clinically and radiologically, the radiologist should be familiar with this entity.
View Article and Find Full Text PDFDistribution Patterns of Benign and Malignant Bone and Soft Tissue Tumors and Tumor-like lesions in the Hindfoot and Ankle: A 12.5-year Analysis.
In Vivo
August 2024
Department of Orthopedics and Sports Orthopedics, Technical University of Munich, Klinikum Rechts der Isar, Munich, Germany.
Article Synopsis
- This study analyzes the distribution and types of benign and malignant lesions in the hindfoot and ankle over a 12.5-year period, showing that the majority of cases (81.9%) were soft tissue lesions, with a smaller portion being osseous lesions (18.1%).
- Of the reviewed cases, 77 were benign and 9 were malignant, leading to an overall malignancy rate of 8.6%, with malignant cases seen primarily in older patients (mean age of 59.2 years).
- The findings emphasize the importance of accurate imaging and pathology assessment, as benign lesions are more common but malignant tumors can present similarly and should be taken seriously, especially in ambiguous cases
[Auricular and periauricular pathologies in the ENT department of Sylvanus Olympio Teaching Hospital in Lome (Togo)].
Med Trop Sante Int
June 2024
Service d'oto-rhino-laryngologie (ORL) et de chirurgie cervicofaciale, Centre hospitalier universitaire Sylvanus Olympio, 198, Rue de l'Hôpital Tokoin Hôpital, BP 57 Lomé, Togo.
Article Synopsis
- The study examines various auricular and peri-auricular pathologies over a five-year period, focusing on their epidemiological and clinical features.
- The research involved 159 patients, predominantly young adults and children, with a mix of conditions such as benign tumors, trauma, and congenital issues.
- Management strategies are tailored to the specific type of lesion, balancing both functional and aesthetic concerns.
Case report: Bilateral optic nerve sheath meningocele: clinical aspects.
Front Ophthalmol (Lausanne)
May 2024
Institut Clínic d'Oftalmologia, Hospital Clinic, Barcelona, Spain.
Optic nerve sheath meningocele is an enlargement of the sheath itself, consisting of a collection of cerebrospinal fluid along the perineural space. It should be considered primary if it is not associated with orbital-cerebral neoplasm or with cranio-orbital junction malformations. We report three cases of bilateral primary idiopathic optic nerve sheath meningocele, two of them with gradual vision loss.
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