AI Article Synopsis
- Parastomal hernia (PSH) is a common issue in patients who undergo ileal conduit urinary diversion after surgery for bladder cancer (radical cystectomy).
- A study involving 104 patients compared two types of ileal conduit: a modified version that keeps it outside the peritoneum and a conventional one.
- The modified conduit group showed a significantly lower incidence of PSH (11.5% compared to 28.8%) after 32 months, indicating that this method may effectively reduce the risk of hernias.
Article Abstract
Parastomal hernia (PSH) is a common complication in patients receiving ileal conduit urinary diversion after radical cystectomy. In this randomized controlled clinical trial, we validate our previous finding that extraperitonealization of ileal conduit decreases incidence of PSH. In total, 104 consecutive patients undergoing radical cystectomy at Sun Yat-sen University Cancer Center are randomized 1:1 to receive either modified (extraperitonealized) ileal conduit (n = 52) or conventional ileal conduit (n = 52). Primary endpoint is incidence of radiological PSH during follow-up. Incidence of radiological PSH is lower in the modified group than in the conventional group (11.5% vs. 28.8%; p = 0.028) after a median follow-up of 32 months, corresponding to a hazard ratio of 0.374 (95% confidence interval: 0.145-0.965, p = 0.034) in the modified conduit group. The results support our previous finding that extraperitonealization of the ileal conduit is effective for reducing risk of PSH in patients receiving ileal conduit diversion.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10829722 | PMC |
| http://dx.doi.org/10.1016/j.xcrm.2023.101343 | DOI Listing |
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