Bambus[6]urils and biotin[6]urils are macrocycles with an exceptional affinity for inorganic anions. Here, we investigated statistical condensation of 2,4-dibenzylglycoluril and d-biotin, monomers of the corresponding macrocycles, to prepare the enantiomerically pure macrocycle containing a single d-biotin and five glycoluril units. Host-guest properties of in chloroform solution and solid state were investigated. The macrocycle bearing a single functional group was employed in the formation of [1]rotaxane utilizing reversible covalent bonds.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10789090 | PMC |
| http://dx.doi.org/10.1021/acs.orglett.3c03715 | DOI Listing |
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