In the ever-evolving realm of agriculture, the convoluted interaction between plants and microorganisms have assumed paramount significance. Fungal endophytes, once perceived as mere bystanders within plant tissues, have now emerged as dynamic defenders of plant health. This comprehensive review delves into the captivating world of fungal endophytes and their multifaceted biocontrol mechanisms. Exploring their unique ability to coexist with their plant hosts, fungal endophytes have unlocked a treasure trove of biological weaponry to fend off pathogens and enhance plant resilience. From the synthesis of bioactive secondary metabolites to intricate signaling pathways these silent allies are masters of biological warfare. The world of fungal endophytes is quite fascinating as they engage in a delicate dance with the plant immune system, orchestrating a symphony of defense that challenges traditional notions of plant-pathogen interactions. The journey through the various mechanisms employed by these enigmatic endophytes to combat diseases, will lead to revelational understanding of sustainable agriculture. The review delves into cutting-edge research and promising prospects, shedding light on how fungal endophytes hold the key to biocontrol and the reduction of chemical inputs in agriculture. Their ecological significance, potential for bioprospecting and avenues for future research are also explored. This exploration of the biocontrol mechanisms of fungal endophytes promise not only to enrich our comprehension of plant-microbe relationships but also, to shape the future of sustainable and ecofriendly agricultural practices. In this intricate web of life, fungal endophytes are indeed the unsung heroes, silently guarding our crops and illuminating a path towards a greener, healthier tomorrow.
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http://dx.doi.org/10.3389/fmicb.2023.1280258 | DOI Listing |
Environ Microbiol Rep
February 2025
Department of Systematic and Environmental Botany, Faculty of Biology, Adam Mickiewicz University, Poznań, Poland.
The fungus Beauveria felina is often classified as one of the so-called good biocontrol agents. However, no information is available about the growth of this entomopathogenic fungus in the presence of other endophytic fungi, which are usually found in plant tissues. Effects of fungal interactions vary from inhibiting the activity of a biocontrol agent to stimulating its effect on the targeted pathogen.
View Article and Find Full Text PDFPest Manag Sci
January 2025
Department of Plant Pathology and Weed Research, ARO-the Volcani Institute, Rishon LeZion, Israel.
Background: Fungal plant diseases cause major crop losses. Phytopathogenic fungi's ability to evolve resistance to fungicides, alongside ongoing prohibition of such agents by the European Commission because of their pronounced adverse effects on human health and the environment, make their control a challenge. Moreover, the development of less perilous fungicides is a complex task.
View Article and Find Full Text PDFWorld J Microbiol Biotechnol
January 2025
Biotechnology Division, CSIR-Institute of Himalayan Bioresource Technology (IHBT), Palampur, HP, 176061, India.
Understanding the change in plant-associated microbial diversity and secondary metabolite biosynthesis in medicinal plants due to their cultivation in non-natural habitat (NNH) is important to maintain their therapeutic importance. Here, the bacterial endomicrobiome of Podophyllum hexandrum plants of natural habitat (NH; Kardang and Triloknath locations) and NNH (Palampur location) was identified and its association with the biosynthesis of podophyllotoxin (PTOX) was revealed. Rhizomes (source of PTOX) of plants of NH had highest endophytic bacterial diversity compared to NNH-plants.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Botany, MMV, Banaras Hindu University, Varanasi, 221005, India.
The research highlights the importance of exploring endophytic microbiomes of medicinal plants to uncover their potential for secondary metabolite production and their role in the biosynthesis of host-derived compounds. This study was aimed to isolate leaf endophytic bacteria of Rauvolfia serpentina, investigate their antibacterial, antioxidant potentials and detect host-origin compound reserpine using Reverse Phase High-Performance Liquid Chromatography (RPHPLC). Untargeted analysis via Ultra High-Performance Liquid Chromatography-High-Resolution Mass Spectrometry (UHPLC-HRMS/MS) was conducted for profiling main phytochemicals in the leaves and to explore potential bioactive compounds in bacterial extracts.
View Article and Find Full Text PDFEnzyme Microb Technol
January 2025
College of Biological and Food Engineering, Anhui Polytechnic University, Wuhu, Anhui 241000, China; Anhui Engineering Laboratory for Industrial Microbiology Molecular Breeding, Anhui Polytechnic University, Wuhu, Anhui 241000, China. Electronic address:
Recent years have seen an increase in the development of functional Jiaosu products, including eco-friendly Jiaosu and antimicrobial healthcare fermentation products. As a result, research on the antibacterial activity of Jiaosu has attracted attention. In the present study, the endophytic yeast WCF016, which exhibits antibacterial activity against Escherichia coli and Staphylococcus aureus, was isolated from the peel of water chestnut and identified as Candida sake via morphological and phylogenetic analyses based on 26S rDNA D1/D2 region sequencing.
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