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Mycochemical composition and antioxidant activity of root endophytic aquatic hyphomycetes isolated from the riparian area of Kumaun Himalaya, India. | LitMetric

AI Article Synopsis

  • Endophytic fungi are important sources of bioactive compounds, and this study focused on fungal isolates from the roots in Nainital's riparian area.
  • The chemical analysis revealed 32 compounds, with key ones including 1,2-Benzenedicarboxylic acid, diethyl ester, and Bis(2-ethylhexyl) phthalate identified through GC-MS.
  • The antioxidant capacity was tested using DPPH, MCA, and FRAP assays, showing effective antioxidant activity with notable IC50 values and a measurement of 436.71 ± 9.3 mg AAE/g in FRAP assays.

Article Abstract

Endophytic fungi are essential sources of various bioactive natural compounds. The present study is aimed to investigate the chemical composition and antioxidant compounds of the root endophytic aquatic hyphomycetous fungi isolated from the roots of growing in the riparian area of Nainital, Kumaun Himalaya. The chemical profiling was done by GC-MS analysis. The presence of 32 compounds characterised the fungal extract. 1, 2-Benzenedicarboxylic acid, diethyl ester; Bis(2-ethylhexyl) phthalate; and Bicyclo [3.2.1]octan-4-on-1-carbonsaeure,6-(6,10dimethyl-1,5,9-undecatrien-2-yl)-8-methyl-, ethyl ester were reported as major compounds in the ethyl acetate extract of . The antioxidant capacity of the extract was assessed by DPPH, MCA, and FRAP assay. In antioxidant analysis, the ethyl acetate extract of presents IC50, 42.34 µg/ml, and 46.90 µg/ml using DPPH and MCA, respectively. The tested extract also showed effective antioxidant activity 436.71 ± 9.3 mg AAE/g of the dry extract using FRAP assay.

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Source
http://dx.doi.org/10.1080/14786419.2023.2297406DOI Listing

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