Prolonged oestrogenic endometrium and persistent oestrogenic endometrium are frequent pathological states which have in common a variable degree delay or an absence of apparition of histological signs of luteal impregnation. In fact these two main states include several kinds of lesion; in our experience this point of view, which is an artificial division, is a too static one. We have to consider all the possible states to see the evolution of the whole. In this work, we have performed a cautious mounting of the different phases to get a dynamic view of these lesion; with this view one can see with a different lighting luteal insufficiency of the endometrium. In that way numerous secretory dystrophic aspects considered like secretory abnormal endometrium have to be related to prolonged or persistent oestrogenic states of which they are an evolutive variant. This dynamic approach allows to establish clinico-pathological correlations and leads to a best knowledge of hyperplasic endometrium and of treatment and prevention of endometrial hyperplasia.

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