ELTS-Net: An enhanced liver tumor segmentation network with augmented receptive field and global contextual information.

Comput Biol Med

Department of Instrumental and Electrical Engineering, Xiamen University, Fujian 361005, China. Electronic address:

Published: February 2024

AI Article Synopsis

  • The liver is at high risk for late-stage cancer, making early diagnosis crucial; this study introduces ELTS-Net, an enhanced 3D U-Net model aimed at improving liver cancer segmentation.
  • ELTS-Net incorporates dilated convolutions and an attention residual module to better utilize spatial features and capture contextual information in imaging analysis.
  • Evaluation of ELTS-Net on the LiTS2017 dataset shows significant improvements in liver and tumor segmentation accuracy over traditional models, demonstrating its potential for aiding clinical diagnosis and treatment.

Article Abstract

The liver is one of the organs with the highest incidence rate in the human body, and late-stage liver cancer is basically incurable. Therefore, early diagnosis and lesion location of liver cancer are of important clinical value. This study proposes an enhanced network architecture ELTS-Net based on the 3D U-Net model, to address the limitations of conventional image segmentation methods and the underutilization of image spatial features by the 2D U-Net network structure. ELTS-Net expands upon the original network by incorporating dilated convolutions to increase the receptive field of the convolutional kernel. Additionally, an attention residual module, comprising an attention mechanism and residual connections, replaces the original convolutional module, serving as the primary components of the encoder and decoder. This design enables the network to capture contextual information globally in both channel and spatial dimensions. Furthermore, deep supervision modules are integrated between different levels of the decoder network, providing additional feedback from deeper intermediate layers. This constrains the network weights to the target regions and optimizing segmentation results. Evaluation on the LiTS2017 dataset shows improvements in evaluation metrics for liver and tumor segmentation tasks compared to the baseline 3D U-Net model, achieving 95.2% liver segmentation accuracy and 71.9% tumor segmentation accuracy, with accuracy improvements of 0.9% and 3.1% respectively. The experimental results validate the superior segmentation performance of ELTS-Net compared to other comparison models, offering valuable guidance for clinical diagnosis and treatment.

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Source
http://dx.doi.org/10.1016/j.compbiomed.2023.107879DOI Listing

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