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Role of Carrot ( L.) Storage Roots in Drought Stress Adaptation: Hormonal Regulation and Metabolite Accumulation.
Metabolites
January 2025
Department of Crop Science, Chungbuk National University, Cheong-ju 28644, Republic of Korea.
Drought stress has become one of the biggest concerns in threating the growth and yield of carrots ( L.). Recent studies have shed light on the physiological and molecular metabolisms in response to drought in the carrot plant; however, tissue-specific responses and regulations are still not fully understood.
View Article and Find Full Text PDFLower urinary tract dysfunction following stroke: From molecular mechanisms to clinical anatomy.
J Biol Methods
September 2024
C.N.S. Alliance Research Group, Athens 19400, Greece.
Bladder dysfunction is a common clinical problem in stroke patients and a strong prognostic factor of disability and exerts an enormous impact on health and economy. The aim of this narrative review was tο examine the pathophysiological mechanisms of lower urinary tract symptoms after stroke, as well as the relevant clinical anatomy. Normal micturition is achieved through complex coordination between brain regions, spinal cord, and peripheral nerves, and anatomic brain connectivity is crucial to lower urinary tract physiology.
View Article and Find Full Text PDFThe molecular pathways leading to GABA and lactic acid accumulation in florets of organic broccoli rabe ( subsp. ) stored as fresh or as minimally processed product.
Hortic Res
January 2025
Institute for Biological Systems, National Research Council (CNR), Via Salaria Km 29,300, 00015 Monterotondo, Rome, Italy.
In the context of organic farming, the introduction of a local product to wider markets and an evaluation of storage effects, metabolic and transcriptomic variations in two broccoli rabe genotypes from production cycles of two different years were studied by comparing florets of stored fresh (SF) and packaged (P) for 4 days with those harvested fresh from the field (H). Twenty-five hydrosoluble compounds, including amino acids, carbohydrates, and organic acids, were quantified by untargeted nuclear magnetic resonance (NMR). Principal component analysis produced a neat separation among the three commodity statuses with P being the most divergent and SF closer to H.
View Article and Find Full Text PDFOptimization of γ-Aminobutyric Acid Production in Brown Rice via Prolonged Seed Priming.
Plants (Basel)
December 2024
Fujian Laboratory for Rice Germplasm Innovation and Molecular Breeding, Biotechnology Research Institute, Institute of Crop Sciences, Fujian Academy of Agricultural Sciences, Fuzhou 350001, China.
Germinated whole seeds possess elevated levels of bioactive nutrients; however, their application is hindered by several constraints. The germination process is typically time-consuming, and germinated seeds present challenges in terms of storage and transportation compared to dry seeds. This study introduces a novel processing method for rice, termed prolonged priming (PLP), aiming to combine the benefits of germinated and dry seeds.
View Article and Find Full Text PDFMyeloid cell-specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease.
Sci Transl Med
December 2024
German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.
Article Synopsis
- * In studies using a mouse model lacking the NPC1 protein in immune cells, researchers found significant changes in microglial lipid profiles, increased microglial activity, and symptoms resembling NPC disease, such as lifespan reduction and motor issues.
- * Monitoring translocator protein (TSPO) levels in the blood may be useful for assessing NPC disease progression and treatment response, as shown by changes in TSPO levels following a specific therapy that appeared beneficial for patients.
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