Membranes prepared from the olfactory mucosa of the rat show a high level of adenylate cyclase activity. The activity increases up to 2-fold in the presence of physiologically relevant concentrations of odorants and is inhibited by Ca2+. The level of cyclase activity found is sufficient to explain the speed of olfactory transduction, which occurs on a time scale of tens of milliseconds.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1147457 | PMC |
http://dx.doi.org/10.1042/bj2400605 | DOI Listing |
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