Factors Associated with Spontaneous Preterm Birth after Ultrasound-Indicated Cerclage.

J Pers Med

Institute of New Frontier Research Team, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea.

Published: December 2023

AI Article Synopsis

  • Ultrasound-indicated cerclage (UIC) is a procedure recommended to prevent spontaneous preterm birth (sPTB) in women with a short cervix and a previous history of preterm birth.
  • A study analyzed factors influencing sPTB after UIC, finding that earlier gestational age and shorter cervical length at the time of UIC were linked to higher risks of sPTB.
  • Additional risk factors included elevated preoperative serum inflammatory markers and obesity, while previous preterm birth did not directly increase sPTB risk but raised chances of needing another cerclage.

Article Abstract

Ultrasound-indicated cerclage (UIC) is recommended to prevent spontaneous preterm birth (sPTB) in women with a short cervix at mid-trimester and a history of PTB. We assessed the factors related to sPTB after UIC and determined the corresponding risks. This retrospective cohort study was conducted at a university hospital. UIC was performed between 15 and 26 weeks of gestation in women with a cervical length of <2.5 cm. Univariate and multivariate analyses were used to examine factors associated with sPTB after UIC. An earlier gestational age and shorter cervical length at UIC were associated with sPTB after UIC. While PTB history was not associated with an increased risk of sPTB, it did increase the risk of repeat cerclage after UIC. Higher levels of preoperative serum inflammatory markers and obesity significantly increased the risk of sPTB after UIC. These findings provide helpful guidance for patient counseling and management in predicting the delivery timing after UIC in women with a short cervix in the mid-trimester.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10744759PMC
http://dx.doi.org/10.3390/jpm13121678DOI Listing

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