AI Article Synopsis
- Curcumin, a natural compound from turmeric, has a wide range of health benefits including anti-inflammatory and antioxidant properties.
- It interacts with cellular mechanisms like gene regulation and can neutralize various free radicals, making it promising for health and disease prevention.
- The review aims to explore the electron transfer reactions of curcumin, focusing on its oxidation mechanisms and discussing advanced methods for detecting curcumin in food and supplements.
Article Abstract
Curcumin is a natural polyphenol derived from turmeric () root that has been used for centuries as a spice, coloring agent, and medicine. Curcumin presents anti-inflammatory, antioxidant, anticarcinogenic, antimicrobial, antiviral, antimalarial, hepatoprotective, thrombosuppressive, cardiovascular, hypoglycemic, antiarthritic, and anti-neurodegenerative properties. It scavenges different forms of free radicals and acts on transcription factors, growth factors and their receptors, cytokines, enzymes, and genes, regulating cell proliferation and apoptosis. Curcumin is electroactive, and a relationship between its electron transfer properties and radical-scavenging activity has been highlighted. The objective of this review is to provide a comprehensive overview of the curcumin electron transfer reactions, with emphasis on the controversial aspects related to its oxidation mechanism. The final sections will focus on the electroanalysis of curcumin in natural products, highlighting the most important sensing strategies, based on functional electrodes and nanostructured materials, essential for the development of more efficient in vitro methods of detection and quantification of curcumin in food samples, supplements, and nutripharmaceuticals.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10740878 | PMC |
| http://dx.doi.org/10.3390/antiox12122029 | DOI Listing |
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