AI Article Synopsis
- * The paper reviews how adding various metal ions (like Ag, Zn, Mg, Sr, Sm, and Ce) to HA can enhance its properties, particularly by adding functions like antibacterial effects.
- * It also addresses the challenges faced in using these metal ion-doped HA materials for bone restoration and suggests possible solutions.
Article Abstract
Hydroxyapatite (HA)-based materials are widely used in the bone defect restoration field due to their stable physical properties, good biocompatibility, and bone induction potential. To further improve their performance with extra functions such as antibacterial activity, various kinds of metal ion-doped HA-based materials have been proposed and synthesized. This paper offered a comprehensive review of metal ion-doped HA-based materials for bone defect restoration based on the introduction of the physicochemical characteristics of HA followed by the synthesis methods, properties, and applications of different kinds of metal ion (Ag, Zn, Mg, Sr, Sm, and Ce)-doped HA-based materials. In addition, the underlying challenges for bone defect restoration using these materials and potential solutions were discussed.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10741145 | PMC |
| http://dx.doi.org/10.3390/bioengineering10121367 | DOI Listing |
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