Groundwater is widely recognized as a vital source of fresh drinking water worldwide. However, the rapid, unregulated population growth and increased industrialization, coupled with a rise in human activities, have significantly harmed the quality of groundwater. Changes in the local topography and drainage systems in an area have negative impacts on both the quality and quantity of groundwater. This underscores the critical need to assess the susceptibility of groundwater to pollution and implement measures to mitigate these risks. The water quality index (WQI) is an approach that simulates the water quality at peculiar locations for a particular period of time. The artificial neural network (ANN) model approach is such an idealistic methodology that can be utilized for WQI development and provides better results for specific locations in optimum time. Therefore, the goal of the current study is to provide a unique way for using artificial neural networks (ANN) to characterize the groundwater quality of Delhi Metropolitan City, India. In order to make the water fit for residential and drinking use, the research also pinpoints the geographical variability and spots where the contaminated region has to be sufficiently cleaned. A minimum WQI of 41.51 was obtained at the Jagatpur location while a maximum value of 779.01 was at the Peeragarhi location. During the training phase, the results obtained using the ANN model were highly favorable, demonstrating a strong association with an R-value of 98.10%, thus highlighting the program's exceptional efficiency. However, in accordance with the correlation regression findings, the prediction outcomes of the ANN model in testing are observed to be an R-value of 99.99-100%. This study confirms the promise and advantages of employing advanced artificial intelligence in managing groundwater quality in the studied area.
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http://dx.doi.org/10.1007/s11356-023-31584-4 | DOI Listing |
Blood
January 2025
Cleveland Clinic, Cleveland, Ohio, United States.
Antibodies to β2-glycoprotein I (β2GPI) cause thrombosis in antiphospholipid syndrome, however the role of β2GPI in coagulation in vivo is not understood. To address this issue, we developed β2GPI-deficient mice (Apoh-/-) by deleting exon 2 and 3 of Apoh using CRISPR/Cas9 and compared the development of thrombosis in wild-type (WT) and Apoh-/- mice using rose bengal and FeCl3-induced carotid thrombosis, laser-induced cremaster arteriolar injury, and inferior vena cava (IVC) stasis models. We also compared tail bleeding times and activation of platelets from WT and Apoh-/- mice in the absence and presence of β2GPI.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
February 2025
Department of Computer Science, University of Manchester, Manchester M13 9PL, United Kingdom.
The preference for simple explanations, known as the parsimony principle, has long guided the development of scientific theories, hypotheses, and models. Yet recent years have seen a number of successes in employing highly complex models for scientific inquiry (e.g.
View Article and Find Full Text PDFAnn Clin Transl Neurol
January 2025
Department of Neuro-Urology, Balgrist University Hospital, University of Zürich, Zürich, Switzerland.
Objective: To characterize structural integrity of the lumbosacral enlargement and conus medullaris within one month after spinal cord injury (SCI).
Methods: Lumbosacral cord MRI data were acquired in patients with sudden onset (<7 days) SCI at the cervical or thoracic level approximately one month after injury and in healthy controls. Tissue integrity and loss were evaluated through diffusion tensor (DTI) and T2*-weighted imaging (cross-sectional area [CSA] measurements).
ACS Sens
January 2025
Department of Engineering Physics, McMaster University, 1280 Main Street West, L8S 4L8 Hamilton, Ontario, Canada.
Current approaches for classifying biosensor data in diagnostics rely on fixed decision thresholds based on receiver operating characteristic (ROC) curves, which can be limited in accuracy for complex and variable signals. To address these limitations, we developed a framework that facilitates the application of machine learning (ML) to diagnostic data for the binary classification of clinical samples, when using real-time electrochemical measurements. The framework was applied to a real-time multimeric aptamer assay (RT-MAp) that captures single-frequency (12.
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