The Relationship Between Glycated Hemoglobin and Time in Range in a Pediatric Population.

In adults with type 1 diabetes (T1D), time in range (TIR) [70-180 mg/dL] has been proposed as an additional metric besides glycated hemoglobin (HbA1c). This retrospective monocentric cohort study determined the correlation between HbA1c and TIR during the 2, 4, and 12 weeks (TIR, TIR, and TIR) before consultation in a pediatric T1D population. A total of 168 children with T1D were included. Continuous glucose monitoring data, HbA1c, and demographic variables were collected. We found strong linear correlations between HbA1c and TIR ( = -0.571), HbA1c and TIR ( = -0.603), and between HbA1c and TIR ( = -0.624). A strong correlation exists between TIR and TIR, HbA1c and time above range (TAR), and between TIR and TAR at different time points. In conclusion, a strong correlation was found between HbA1c and TIR, making TIR a potentially complementary metric to HbA1c. TIR seems a viable alternative to TIR. TAR also seems promising in assessing glycemic control.