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Identifying risk factors and developing a nomogram for HFNC failure in patients with hypercapnic acute respiratory failure.
Am J Emerg Med
January 2025
Department of Emergency Department, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou 225001, China. Electronic address:
Background: Currently, there is a deficiency in nomograms specifically designed for predicting the failure of high-flow nasal cannula (HFNC) oxygen therapy in patients with hypercapnic acute respiratory failure (hypercapnic ARF). The aim of this retrospective study is to develop and evaluate a nomogram that assesses the risk of HFNC failure in this patient population.
Methods: Patients with ARF and hypercapnia (PaCO ≥ 45 mmHg in the initial arterial blood gas) who received HFNC in the intensive care unit (ICU) from January 1, 2020 to December 31, 2023 were enrolled in this study.
The expression of MALAT1, plasma brain natriuretic peptide, and Tei index in sepsis-induced myocardial injury.
J Cardiothorac Surg
January 2025
Emergency and Critical Care Center, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, China.
Purpose: We sought to investigate the expression of MALAT1, plasma brain natriuretic peptide, and Tei index in sepsis-induced myocardial injury.
Methods: The current retrospective analysis focused on 146 sepsis patients admitted to our hospital from February 2021 to March 2023. Based on the presence or absence of myocardial injury, the patients were divided into two groups: the sepsis group (n = 80) and the sepsis-induced myocardial injury group (n = 66).
Respiratory-rate Oxygenation index for Predicting Noninvasive Ventilation Associated With High-flow Nasal Cannula Failure in Acute Respiratory Failure Due to SARS-CoV-2.
J Intensive Care Med
February 2025
Sorbonne University, GRC 29, AP-HP, DMU DREAM, Department of Anaesthesiology and Critical Care, Pitié-Salpêtrière Hospital, Centre Hospitalier Universitaire Pitié-Salpêtrière, Paris, France.
Purpose: The respiratory rate-oxygenation (ROX) index is used to predict high-flow nasal cannula (HFNC) success in acute respiratory failure, including in Coronavirus disease 2019 (COVID-19) patients. However, no study has described its performance to predict failure of alternating sessions of noninvasive ventilation (NIV) and HFNC in severe COVID-19 patients.
Material And Methods: We conducted a monocentric retrospective cohort study.
Early physiologic changes after awake prone positioning predict clinical outcomes in patients with acute hypoxemic respiratory failure.
Intensive Care Med
December 2024
Department of Medicine, Interdepartmental Division of Critical Care Medicine, Sinai Health System and University Health Network, University of Toronto, Toronto, Canada.
Purpose: The optimal physiologic parameters to monitor after a session of awake prone positioning in patients with acute respiratory failure are not well understood. This study aimed to identify which early physiologic changes after the first session of awake prone positioning are linked to the need for invasive mechanical ventilation or death in patients with acute respiratory failure.
Methods: We performed a secondary analysis of a prospective cohort study of adult patients with acute respiratory failure related to coronavirus disease 2019 (COVID-19) treated with awake prone positioning.
Predictors of Poor Outcomes in Chronic Obstructive Pulmonary Disease (COPD) Patients Admitted to the Emergency Department With COVID-19: A Prospective Study.
Cureus
October 2024
Emergency Medicine, Ümraniye Training and Research Hospital, Istanbul, TUR.
Objectives Long-term consequences of COVID-19 in the post-pandemic era are still being investigated. Despite the growing data on COVID-19, there remains a lack of information regarding predictors of poor outcomes among chronic obstructive pulmonary disease (COPD) patients with COVID-19. Methods A single-center prospective cohort study was conducted with a total of 172 adult COPD patients with COVID-19 pneumonia included.
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