The inherent self-repair abilities of the body often fall short when it comes to addressing injuries in soft tissues like skin, nerves, and cartilage. Tissue engineering and regenerative medicine have concentrated their research efforts on creating natural biomaterials to overcome this intrinsic healing limitation. This comprehensive review delves into the advancement of such biomaterials using substances and components sourced from marine origins. These marine-derived materials offer a sustainable alternative to traditional mammal-derived sources, harnessing their advantageous biological traits including sustainability, scalability, reduced zoonotic disease risks, and fewer religious restrictions. The use of diverse engineering methodologies, ranging from nanoparticle engineering and decellularization to 3D bioprinting and electrospinning, has been employed to fabricate scaffolds based on marine biomaterials. Additionally, this review assesses the most promising aspects in this field while acknowledging existing constraints and outlining necessary future steps for advancement.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10744877 | PMC |
| http://dx.doi.org/10.3390/md21120611 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Sticky organisms create underwater biological adhesives driven by interactions between EGF- and GlcNAc- containing polysaccharides.
Nat Commun
January 2025
Division of Environmental Science and Engineering, Pohang University of Science and Technology, Pohang, South Korea.
Marine and terrestrial organisms often utilise EGF/EGF-like domains in wet adhesives, yet their roles in adhesion remain unclear. Here, we investigate the Barbatia virescense byssal system and uncover an oxidation-independent, reversible, and robust adhesion mechanism where EGF/EGF-like domain tandem repetitions in adhesive proteins bind robustly to GlcNAc-based biopolymer. EGF/EGF-like-domain-containing proteins demonstrate over three-fold superior underwater adhesion to chitosan compared to the well-known strongest wet-adhesive proteins, mefp-5, and suckerin, when adhering to mica in an surface forces apparatus-based measurement.
View Article and Find Full Text PDFBiocompatibility of Novel Marine Collagen on Periodontal Ligament Fibroblasts: A Pathway to Enhanced Regenerative Therapies.
Cell Biochem Funct
January 2025
Department of Pharmacy, Hajvery University, Lahore, Pakistan.
Body wall of sea cucumber Bohadschia bivittate contains a protein consisting of highly insoluble collagen fibers. We aimed to evaluate the biocompatibility and cytotoxicity of nonirradiated or γ-irradiated pepsin soluble collagen (PSC) extracted from Bohadschia bivittata on human periodontal ligament fibroblasts cells. The MTT assay showed significant increase in the cell viability values indicating that PSC is noncytotoxic.
View Article and Find Full Text PDFEvaluating the feasibility of estimating particulate mass emissions of older-model diesel vehicle using smoke opacity measurements.
Sci Rep
December 2024
Clean Energy Technologies Research Institute (CETRI), Process Systems Engineering, Faculty of Engineering & Applied Science, University of Regina, 3737 Wascana Parkway, Regina, SK, S4S 0A2, Canada.
Real-world emissions of particulate matter (PM) and smoke opacity were studied for an older-model diesel pickup truck during four types of driving tests, namely fixed-point test, snap-acceleration test, road test, and hill road test (uphill/downhill). A portable emissions measurement system (PEMS) and an opacimeter were used to measure real-time concentrations of PM and smoke opacity, respectively, and simultaneously. Correlation analysis showed a significant positive association between PM and opacity, suggesting the feasibility of using an opacimeter to estimate PM mass emissions from diesel vehicles.
View Article and Find Full Text PDFSAM-dPCR: Accurate and Generalist Nuclei Acid Quantification Leveraging the Zero-Shot Segment Anything Model.
Adv Sci (Weinh)
December 2024
Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
Digital PCR (dPCR) has transformed nucleic acid diagnostics by enabling the absolute quantification of rare mutations and target sequences. However, traditional dPCR detection methods, such as those involving flow cytometry and fluorescence imaging, may face challenges due to high costs, complexity, limited accuracy, and slow processing speeds. In this study, SAM-dPCR is introduced, a training-free open-source bioanalysis paradigm that offers swift and precise absolute quantification of biological samples.
View Article and Find Full Text PDFDevelopment of Novel Squid Gladius Biomaterials for Cornea Tissue Engineering.
Mar Drugs
November 2024
Tissue Engineering Group, Department of Histology, Faculty of Medicine, University of Granada, E18016 Granada, Spain.
Cornea tissue engineering is strictly dependent on the development of biomaterials that fulfill the strict biocompatibility, biomechanical, and optical requirements of this organ. In this work, we generated novel biomaterials from the squid gladius (SG), and their application in cornea tissue engineering was evaluated. Results revealed that the native SG (N-SG) was biocompatible in laboratory animals, although a local inflammatory reaction was driven by the material.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!