One-pot synthesis of structurally diverse sulfurized/selenated 4-aminopyrimidines has been reported -BuOK/KSO-promoted four-component reaction of mixed nitriles and disulfides/diselenides. Mechanistic studies indicate that the reaction proceeds through radical and ionic pathways, and an alkenyl sulfide serves as a key intermediate.
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| http://dx.doi.org/10.1039/d3cc05416k | DOI Listing |
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