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Felbamate urolithiasis. | LitMetric

Felbamate urolithiasis.

BMJ Case Rep

Department of Urology, The University of Iowa Hospitals and Clinics, Iowa City, lowa, USA.

Published: December 2023

Drug-induced nephrolithiasis is an important consideration in recurrent stone formers with polypharmacy. While felbamate nephrolithiasis has previously been published in the paediatric population, we present the oldest published case of a felbamate stone in an adult, a man in his 30s with Lennox-Gastaut syndrome. Even with moderate dosing, high drug serum levels can occur. Performing at least one stone analysis remains a critical component to care in these patients. Urologists should have a high index of suspicion for drug stone when stone analysis returns indeterminate characterisation in the absence of infection. Close communication with neurology is key to preventing recurrent stone disease.

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Source
http://dx.doi.org/10.1136/bcr-2022-253883DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10749159PMC

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