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Global mean sea level likely higher than present during the holocene.
Nat Commun
December 2024
Lamont-Doherty Earth Observatory, Columbia University, New York, NY, USA.
Global mean sea-level (GMSL) change can shed light on how the Earth system responds to warming. Glaciological evidence indicates that Earth's ice sheets retreated inland of early industrial (1850 CE) extents during the Holocene (11.7-0 ka), yet previous work suggests that Holocene GMSL never surpassed early industrial levels.
View Article and Find Full Text PDFBackground: An overview of internationally published literature on what works for co-production in youth mental health services is missing, despite a practice and policy context strongly recommending this approach. This rapid realist review develops a theory about how and why co-production methods in youth mental health services work, for whom and in which circumstances.
Methods: Relevant evidence was synthesised to develop Context-Mechanism-Outcome configurations (CMOs) that can inform policy and practice.
Investigation of bidirectional causal association between temporomandibular disorders and five mental disorders.
Arch Oral Biol
December 2024
College & Hospital of Stomatology, Anhui Medical University, Key Lab. of Oral Diseases Research of Anhui Province, Hefei 230032, China. Electronic address:
Objective: This study utilized two-sample Mendelian randomization (TSMR) to investigate the bidirectional causal associations between temporomandibular disorders (TMD) and five mental disorders.
Methods: Single-nucleotide polymorphisms (SNPs) linked to TMD were extracted from the Genome-Wide Association Studies (GWAS) database. The SNPs selected as instrumental variables (IVs) were required to have strong associations with the exposure phenotype and to meet the assumptions of Mendelian randomization (MR) analysis.
Higher Versus Lower Protein Delivery in Critically Ill Patients: A Systematic Review and Bayesian Meta-Analysis.
Crit Care Med
December 2024
Department of Intensive Care Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.
Objectives: Recent multicenter trials suggest that higher protein delivery may result in worse outcomes in critically ill patients, but uncertainty remains. An updated Bayesian meta-analysis of recent evidence was conducted to estimate the probabilities of beneficial and harmful treatment effects.
Data Sources: An updated systematic search was performed in three databases until September 4, 2024.
Psychometric validation of the Diagnostic Assessment Research Tool: Alcohol use disorder module.
Alcohol Alcohol
November 2024
Peter Boris Centre for Addictions Research, St Joseph's Healthcare Hamilton and McMaster University, 100 West 5th Street, Hamilton, Ontario L8N 3K7, Canada.
Aims: Structured clinical interviewing is considered the gold standard in psychiatric diagnosis. The Diagnostic Assessment Research Tool (DART) is a novel modularized, non-copywritten, semi-structured interview; however, no studies have examined the psychometric properties of its alcohol use disorder (AUD) module. The primary aims of this study were to: (i) validate the factor structure of the DART AUD module and (ii) examine measurement invariance across several key demographic and subgroup factors.
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