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| http://dx.doi.org/10.14309/crj.0000000000001217 | DOI Listing |
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Warfarin-ciprofloxacin interaction complicated by subcapsular renal hematoma and retroperitoneal hematoma: Case report.
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Consultant of Endourology and MIS at King Fahad Hospital of University, College of Medicine Imam Abdulrahman bin Faisal University, Saudi Arabia.
Spontaneous, non-traumatic bleeding into the subcapsular and perirenal space is a rare and potentially fatal condition known as Wunderlich syndrome (WS). It has a variety of causes including the usage of anticoagulation. Many anticoagulants including warfarin can interact with other medication and lead to potentially fatal complications, Herein, we report a case of a 47 year old female on warfarin who developed subcapsular renal hematoma and retroperitoneal hematoma after the completion of ciprofloxacin treatment course.
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Department of Pathology, All India Institute of Medical Sciences Bhopal, Bhopal, Madhya Pradesh, India.
Introduction: Neuroblastoma is an embryonic tumor of the peripheral sympathetic nervous system. It is the most common extracranial solid tumor of childhood and accounts for up to 15% of all pediatric cancer fatalities. The manifestation of neuroblastoma is variable depending on the location of the tumor and the presence or absence of paraneoplastic syndromes.
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Department of Gastroenterology, Mulei County People's Hospital, Mulei, China.
Rationale: Spontaneous retroperitoneal hematoma (SRH) is a rare but potentially fatal condition, often associated with anticoagulation therapy. With the global prevalence of COVID-19 and the widespread use of anticoagulants in its management, there is an increasing need to recognize rare but serious complications like SRH. This case report aims to emphasize the importance of early recognition and intervention of SRH in patients with COVID-19 undergoing anticoagulation therapy, to improve patient outcomes and reduce mortality.
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Article Synopsis
- * He underwent a left radical orchiectomy and began chemotherapy with bleomycin, etoposide, and cisplatin, developing signs of tumor lysis syndrome (TLS) before treatment.
- * The patient was treated with IV normal saline and allopurinol to stabilize his uric acid and potassium levels, highlighting the need for monitoring TLS in patients with extensive tumor burden prior to chemotherapy.
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