Response of low HER2-expressing ovarian carcinosarcoma to trastuzumab deruxtecan, a case report.

Gynecol Oncol Rep

Section of Gynecologic Oncology, Women's Health Institute, Cleveland Clinic, A-81, 9500 Euclid Ave., Cleveland, OH 44195, USA.

Published: December 2023

•Treatment options are limited for recurrent ovarian carcinosarcoma (OCS).•A patient with HER2 1 + IHC and negative FISH amplification was treated with trastuzumab deruxtecan.•A durable partial response was achieved, suggesting a possible treatment option for OCS patients with HER2 expression.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10730426PMC
http://dx.doi.org/10.1016/j.gore.2023.101311DOI Listing

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