Gene of the month: .

J Clin Pathol

Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA

Published: January 2024

The V-set and transmembrane domain containing 2A ( gene is located on chromosome 7. In the physiological state, VSTM2A regulates preadipocyte cell differentiation. is highly expressed in normal human brain tissue and minimally expressed in other normal tissues. Mucinous tubular and spindle cell carcinoma (MTSCC) of the kidney is a distinct renal tumour subtype with signature chromosomal copy number alterations and an indolent outcome in the majority of cases. overexpression is highly enriched in this renal cancer subtype and has been shown to have potential diagnostic value in distinguishing MTSCC from renal tumours with overlapping histological appearances.

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Source
http://dx.doi.org/10.1136/jcp-2023-208839DOI Listing

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