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[Aspirin reduces lung inflammatory response in acute lung injury/acute respiratory distress syndrome: a Meta-analysis based on animal experiments].
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
December 2024
Department of Intensive Care Unit, the Affiliated Hospital of Guizhou Medical University, Guiyang 550004, Guizhou, China. Corresponding author: Shen Feng, Email:
Objective: To systematically evaluate the impact of aspirin on the pulmonary inflammatory response in animal models of acute lung injury/acute respiratory distress syndrome (ALI/ARDS).
Methods: Experimental research on aspirin therapy or prevention of ALI/ARDS in animal models were searched in PubMed, Web of Science, Cochrane library, Embase, China biology medicine, CNKI, Wanfang, VIP. The search time limit was from the establishment of the database to July 17, 2023.
Role of Antiplatelets and Anticoagulation Therapies in Pregnancy.
J Clin Med
December 2024
Division of Cardiology, Department of Medicine, NewYork-Presbyterian Hospital-Weill Cornell Medicine, New York, NY 10021, USA.
Thrombosis is an important cause of morbidity and mortality worldwide. Pregnancy is a hypercoagulable state, and thrombotic complications in pregnancy are a major cause of maternal and fetal morbidity and mortality. Current guidelines support the selective use of aspirin, heparin, and warfarin in pregnant women.
View Article and Find Full Text PDFAntiplatelet Effects of a Combination of Sappan Wood ( L.) and Red Ginger () Extracts in a High-Fat Diet-Induced Rat Model.
Adv Pharmacol Pharm Sci
December 2024
Laboratory of Pharmacology-Toxicology, Faculty of Pharmacy, Universitas Indonesia, UI Depok Campus, Depok 16424, West Java, Indonesia.
Antithrombotic medications, including antiplatelet agents, are standard treatments for patients with hyperlipidemia who have a high risk of developing cardiovascular disease (CVD). The ongoing exploration of new antiplatelet agents with minimal bleeding effects is crucial, including the investigation of potential compounds derived from natural products. This study intended to evaluate the antiplatelet effects of a combined extract of sappan wood ( L.
View Article and Find Full Text PDFStudy of the Analgesic Activity of the Aqueous and Methanolic Extracts of Fresh Rhizome of Zingiber officinale in Wistar Rats.
Cureus
November 2024
Department of Pharmacology, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, IND.
Introduction The study was done to evaluate the analgesic activity of the aqueous and methanolic extracts of fresh rhizome of . The study objectives included evaluating and comparing the analgesic activity of both extracts at two different doses with that of the standard drug (aspirin) in Wistar rats using the rat tail-flick method. Method The study was conducted after receiving approval from the animal ethics committee.
View Article and Find Full Text PDFPerioperative aspirin and coronary artery bypass graft surgery: An updated meta-analysis of randomized controlled trials.
Surgery
December 2024
Discipline of Surgery, University of Adelaide, Adelaide, Australia; Australian Safety and Efficacy Register of New Interventional Procedures-Surgical, Royal Australasian College of Surgeons, Adelaide, Australia; Research, Audit and Academic Surgery, Royal Australasian College of Surgeons, Adelaide, Australia.
Background: The decision to continue aspirin before elective coronary artery bypass graft surgery remains contentious because of competing thrombotic and bleeding risks. We performed a contemporary systematic review and meta-analysis to compare outcomes between patients undergoing coronary artery bypass grafting who stopped and continued aspirin before surgery.
Methods: PubMed, MEDLINE, and CENTRAL databases were searched from inception to 4 October 2023 for randomized controlled trials comparing patients undergoing coronary artery bypass grafting who continued preoperative aspirin with those who discontinued before surgery.
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